Transcription Factor Scan Identifies Genetic Cause for Inherited Blindness.
Multinational team effort of Regensburg´s Institute of Human Genetics, Washington University in St. Louis, other partners, and Genomatix elucidated a transcriptional network in photoreceptors and thereby identified a novel retinal disease gene
22-Nov-2010 -
Retinitis pigmentosa is an inherited eye disorder characterized by progressive loss of vision that in many instances leads to legal blindness at the end stage.
In a ChIP-Seq based approach, the researchers identified a key regulatory role of the transcription factor Crx (Cone-rod homeobox) in ...
blindness
chromatin
Expression
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