Heptares generates new insight into caffeine's molecular pharmacology to drive design of next-generation CNS therapeutics
First 3-D X-ray Co-structures of Caffeine and other Xanthines Bound to G-Protein Coupled Receptor (GPCR) Published in the Journal Structure
05-Sep-2011 -
The journal Structure has published data from researchers at Heptares Therapeutics elucidating the molecular pharmacology of caffeine and its interaction with G-protein coupled receptors (GPCRs). Caffeine is known to inhibit adenosine receptors, a subfamily of GPCRs widely expressed in the brain, ...
caffeine
G-proteins
inhibitors
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