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54 Current news about the topic bioavailability


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An effective approach to optimizing medicinal molecules


The search for new medicinal molecules with predetermined properties is a rather complex, expensive and time-consuming process, especially in oncology. Modern science allows us to accelerate this search through the use of computer technology and the introduction of automated processes. In the ...


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Adjustment of drug dose for rheumatoid arthritis by diagnostic method

Determination of the therapeutic window of adalimumab


Collaboration between the Immanuel Klinikum Bernau Herzzentrum Brandenburg, the Rheumazentrum Nord-Brandenburg and BioTeZ demonstrates new ways of treating rheumatoid arthritis. Through the introduction of therapeutic antibodies, the treatment results for rheumatoid arthritis (RA) have been ...


Lonza Acquires Micro-Macinazione

Swiss company expert in the field of microniziation


Lonza has acquired Micro-Macinazione, providing micronization of active ingredients for the pharmaceutical and fine chemical industries. Micro-Macinazione, which had sales of ~ CHF 20 million in 2016, has 120 employees and is based in Monteggio, Switzerland. Micro-Macinazione was purchased from ...


Micron-sized hydrogel cubes show highly efficient delivery of a potent anti-cancer drug


Many potent anti-cancer drugs have major drawbacks -- they fail to mix with water, which means they will have a limited solubility in blood, and they lack selectivity to cancer cells. Researchers at the University of Alabama at Birmingham and Texas Tech University Health Sciences Center have ...


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New perspective for soil clean-up

Microscopic ciliates transport poisonous tar substances


You must use a microscope to spot the new helpers that can assist in biological soil clean-up (bioremediation). They are small, mobile microorganisms, such as the unicellular slipper-shaped ciliates that can be found in stale water in a flower vase, where they feed on bacteria. New results from ...


BASF and Catalent join forces to solve bioavailability challenges


Catalent Pharma Solutions and BASF have entered into a broad collaboration and Open Alliance to provide solutions to overcome bioavailability challenges of new molecular entities with solubility or permeability challenges. The companies aim to combine their expertise to provide pharmaceutical ...


Quotient Clinical and Bend Research Announce Collaboration To Accelerate Advancement of New Medicines


Bend Research Inc. and Quotient Clinical, a business unit of Quotient Bioresearch, announced a nonexclusive collaboration that can speed the advance of compounds to clinical trials and expand options for drug delivery. The collaboration combines Bend Research’s advanced drug formulation ...


Hybrigenics develops new oral formulations of inecalcitol

Hybrigenics seeks patent protection until 2030 for innovative oral formulations optimized for the delivery of high doses of inecalcitol


Hybrigenics announced the filing of a patent application covering new soft gelatin capsules, tablets or drinking solutions optimized for the delivery of high doses of inecalcitol. This pharmaceutical optimization followed the demonstration of safety and the presumption of efficacy of oral doses ...


SoluBest and Dr. Reddy´s Sign Drug Delivery Collaboration to Develop New, Proprietary Formulations


SoluBest has closed a collaboration agreement with Dr. Reddy's Laboratories Ltd. to develop a new, proprietary formulation of one of SoluBest’s pipeline compound.. In return, SoluBest is eligible to upfront, research and milestone and significant royalty payments. Further financial details have ...


Glycotope received regulatory approval for glycooptimized and fully human glycosylated antibody CetuGEX


Glycotope GmbH, has received regulatory approval by German and Italian regulatory authorities for a Phase I study of Glycotope's next generation antibody CetuGEX (GT-MAB 5.2-GEX) for the treatment of various solid cancers. “For Glycotope, the approval of CetuGEX, our 2nd antibody in the clinic, ...


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