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Solar panels for yeast cell biofactories

19-Nov-2018

Genetically engineered microbes such as bacteria and yeasts have long been used as living factories to produce drugs and fine chemicals. More recently, researchers have started to combine bacteria with semiconductor technology that, similar to solar panels on the roof of a house, harvests energy ...

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Insect Antibiotic Provides New Way to Eliminate Bacteria

16-Nov-2018

An antibiotic called thanatin attacks the way the outer membrane of Gram-negative bacteria is built. Researchers at the University of Zurich have now found out that this happens through a previously unknown mechanism. Thanatin, produced naturally by the spined soldier bug, can therefore be used ...

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T3 Pharmaceuticals wins prestigious Falling Walls Venture Award

13-Nov-2018

T3 Pharma, a biotech start-up company of the University of Basel with a focus on immuno-oncology, has been named “2018 Science Start-Up of the Year” by Falling Walls Venture. The award honors the scientist-entrepreneurs for their breakthrough business model in bacterial cancer therapy. The ...

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Searching in soil, scientists find a new way to combat tuberculosis

05-Nov-2018

For decades, doctors have been using antibiotics to fight tuberculosis (TB). And consistently, the microbe responsible for the disease, Mycobacterium tuberculosis, has been fighting back. When confronted with current drugs, such as the antibiotic rifamycin, the bacterium often mutates in ways ...

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Electric shocks used to kill bacteria

Electric fields destroy Listeria without damaging nutrients

25-Oct-2018

Low temperatures and an acidic environment create the ideal conditions for applying an effective method of inactivating Listeria (and other germs) in the processing of whey protein solutions – without destroying valuable nutrients. A team from the University of Natural Resources and Life ...

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New agent against anthrax

Reprogramming of Human Siderocalin to Neutralize Petrobactin

23-Oct-2018

A team led by Professor Arne Skerra at the Technical University of Munich (TUM) has developed an innovative strategy for preventing the anthrax bacterium from absorbing iron, which is crucial for its survival. It does so by neutralizing a special iron complexing agent produced by the bacterium. ...

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Smallest life forms have smallest working CRISPR system

Metagenomic search turns up compact Cas protein ideal for disease diagnostics

22-Oct-2018

An ancient group of microbes that contains some of the smallest life forms on Earth also has the smallest CRISPR gene-editing machinery discovered to date. The peewee protein machinery, dubbed Cas14, is related to but one-third the size of the Cas9 protein, the business end of the revolutionary ...

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The tightest non-aminoglycoside ligand for the bacterial ribosomal RNA A-site

17-Oct-2018

A research group at Tohoku University has made a significant discovery with positive implications for the development of bacteria-fighting drugs. The aminoacyl-tRNA site (A-site) of the 16S RNA decoding region in the bacterial ribosome looks promising for a new era of antibiotic drug ...

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How superbugs rapidly evolve

12-Oct-2018

A scientific breakthrough has revealed a new way that bacteria evolves, thought to be at least 1,000 times more efficient than any currently known mechanism. The insights will help scientists to better understand how superbugs can rapidly evolve and become increasingly antibiotic resistant. The ...

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Know your enemy

An arsenal to fight antibiotic-resistant bacteria

11-Oct-2018

To fight your enemies, it helps to know their weaknesses. And, the more specific your knowledge, the easier it is to undermine their defenses. If your enemy sits safe behind a giant wall, for example, its valuable to know how your foe constructed it, what materials they used, and what cracks you ...

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