T cells - 5 News by Charité
T cells require healthy “power plants”
Some T cells of the immune system are especially sensitive to genetic disturbances within their mitochondrial power plants
07-Jul-2023 - All cells have their own power plants, called mitochondria. There are often more than 100 mitochondria per cell and each possesses their own genome, which in turn contains genes responsible for energy production. If errors creep into these genes, this can cause problems in the cell and result in ...
The fatal role of T cells in COVID-19
Safety mechanism is put out of action
06-Jan-2022 - Scientists from the Berlin Institute of Health at Charité (BIH), together with colleagues from Charité – Universitätsmedizin Berlin and the university hospitals in Bonn and Aachen, have found a type of immune cells that is particularly active in severely ill COVID-19 patients. The CD16 positive T ...
Prior exposure to common cold coronaviruses enhances immune response to SARS-CoV-2
03-Sep-2021 - Researchers from Charité – Universitätsmedizin Berlin, the Berlin Institute of Health at Charité (BIH) and the Max Planck Institute for Molecular Genetics (MPIMG) have shown that certain immune cells, which are found in people previously exposed to common cold coronaviruses, enhance the body’s ...
How the immune system paves the way for SARS-CoV-2
SARS-CoV-2 uses an immune system defense mechanism as a port of entry
22-Feb-2021 - The immune system actually wants to fight SARS-CoV-2 with antiviral signaling molecules. But a research team from Charité and MDC has now shown how such a signaling molecule can promote the replication of the virus. Most people infected with SARS-CoV-2 are able to recover from the disease at home ...
HIV-1: The undercover agent
The AIDS virus HIV-1 goes largely unnoticed by T-cells of the immune system thanks to an ingenious propagation strategy
30-Jul-2020 - Antibodies are not the only protection against viruses: At a much earlier stage, infected cells detect components of a virus with the help of internal sensors and trigger an immune response. This is an element of what is known as innate immunity, and helps prevent viruses from spreading further. ...
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