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Roche to leave S1P1 alliance following comprehensive portfolio review and prioritization
09-Dec-2009 - Actelion Ltd announced that the company has decided to proceed with advanced clinical development with its orally available and selective S1P1 receptor agonist (ACT-128800) in psoriasis. ACT-128800 is already in advanced clinical development for multiple sclerosis, where a dose-finding study has ...
08-Dec-2009 - Antisoma plc announced that positive final data from a phase II trial of AS1413 in patients with secondary acute myeloid leukaemia (secondary AML) were presented at the American Society of Hematology (ASH) meeting in New Orleans. Follow-up of patients has now been completed, and full results are ...
08-Dec-2009 - Galapagos NV announced that it has initiated clinical Phase I development of the first small molecule candidate from its arthritis alliance with GlaxoSmithKline (GSK). For entering the clinic with candidate drug GLPG0555, Galapagos receives a milestone payment of €4 million cash from GSK. Since ...
08-Dec-2009 - Lightlake Therapeutics' experts have been granted ethical approval to begin selecting and gene testing subjects for a trial of a simple, safe and effective treatment for what the World Health Organisation has described as a global epidemic of unhealthy eating and obesity. A Phase II trial for ...
Agreement reached on U.S. approval pathway for Pompe disease treatment
08-Dec-2009 - Genzyme Corporation announced that it will reopen enrollment in the Alglucosidase Alfa Temporary Access Program (ATAP), a program which provides access to treatment for severely affected adults with Pompe disease prior to commercial approval of Lumizyme™ (alglucosidase alfa). Genzyme and the FDA ...
07-Dec-2009 - DermaGen AB - part of the Karolinska Development dermatology and wound healing company Pergamum - announced that Dermagen AB has received promising results from a clinical Phase I/IIa study. DermaGen AB is developing a novel antimicrobial peptide (AMP) treatment for atopic dermatitis. Atopic ...
07-Dec-2009 - Biofrontera announced that the company has today been informed about preliminary results of the final pivotal phase III trial with its leading drug candidate BF-200 ALA. The results show with high statistical significance that 78% of the patients were totally cleared from all actinic keratoses ...
07-Dec-2009 - ExonHit Therapeutics announced that AclarusDx™ Alzheimer’s test (formerly known as EHT Dx21), its blood-based test for the detection of Alzheimer’s disease (AD), is now available as a Research Use Only (RUO) product for pharmaceutical companies and academic centers conducting clinical trials in ...
04-Dec-2009 - The Medicines Company announced that it has received European approval for the use of Angiox® (bivalirudin) as an anticoagulant in patients with heart attacks (so-called ST-segment elevation myocardial infarction (STEMI)) undergoing emergency heart procedures called primary percutaneous coronary ...
04-Dec-2009 - Transgene announced that the U.S. Food & Drug Administration (FDA) has granted Fast Track development designation to its immunotherapy product TG4010 (MVA-MUC1-IL2) for the first-line treatment of advanced non-small cell lung cancer (NSCLC) in combination with chemotherapy. The FDA determined ...
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