Brain tumor spread in the living brain observed live for the first time

Three-photon microscopy reveals: immune cells of the brain actively influence how far the tumor advances

23-Apr-2026 - Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it can infiltrate surrounding brain tissue and spread far beyond the main tumor. Researchers from DZNE, University Hospital Bonn and the Cluster of Excellence “ImmunoSensation” at the ...

Insights into olfactory disorders in Alzheimer's disease

19-Aug-2025 - A diminishing sense of smell can be one of the earliest signs of Alzheimer's disease, even before cognitive impairment occurs. Studies by researchers at the DZNE and Ludwig-Maximilians-Universität München (LMU) provide new insights into this phenomenon. According to the study, the brain's immune ...

Smartphone-assisted “scavenger hunt” identifies people at risk for dementia

Perspectives for early detection

11-Oct-2024 - Researchers from DZNE and Otto von Guericke University Magdeburg have identified individuals with increased risk for dementia using mobility data, recorded during a smartphone-based wayfinding task on the university campus. The findings, reported in the journal “PLOS Digital Health”, show the ...

Blood Testing for so-called MicroRNAs Can Detect Dementia

German-American research team highlights new diagnostic option for Alzheimer’s

23-Sep-2024 - Dementia due to Alzheimer’s disease and its preliminary stage can be detected by measuring so-called microRNAs in blood. Researchers from DZNE in Göttingen, together with US experts from Boston University and the Indiana University School of Medicine, report on this in the scientific journal ...

Scientists Unravel Life-saving Effect of Dexamethasone in COVID-19

New approach for targeted drug development

05-Jul-2024 - Dexamethasone is one of the most important drugs in the treatment of severe COVID-19, but patients respond very differently to the therapy. Researchers at the DZNE and Charité – Universitätsmedizin Berlin have now discovered how the cortisone compound influences the impaired inflammatory response ...

Memory self-test via smartphone can identify early signs of Alzheimer’s disease

German-US research team and Magdeburg-based start-up have proven that memory problems can be recognised using an app

05-Apr-2024 - Dedicated memory tests on smartphones enable the detection of “mild cognitive impairment”, a condition that may indicate Alzheimer’s disease, with high accuracy. Researchers from DZNE, the Otto-von-Guericke University Magdeburg and the University of Wisconsin-Madison in the United States who ...

PFAS in blood are ubiquitous – and they are associated with an increased risk of cardiovascular diseases

Younger people are particularly affected

13-Mar-2024 - Researchers at DZNE provide evidence that traces of the widely used PFAS chemicals in human blood are associated with unfavorable lipid profiles and thus with an increased risk of cardiovascular diseases. The findings are based on data from more than 2,500 adults from Bonn and the Dutch ...

With “Swarming AI” Against COVID and Other Diseases

Network of German research institutions uses pioneering artificial intelligence technology to analyze distributed data

23-Jan-2024 - Several German research centers, universities and university hospitals intend to jointly evaluate decentralized data on COVID-19 by leveraging artificial intelligence (AI). Their approach is based on “Swarm Learning”, a novel AI technology that allows distributed data pools to be analyzed while ...

“Viral relicts” in the Genome Could Fuel Neurodegeneration

Researchers see ancient genes as potential targets for dementia treatment

24-Aug-2023 - Genetic remnants of viruses that are naturally present in the human genome could affect the development of neurodegenerative diseases. Researchers at DZNE come to this conclusion on the basis of studies on cell cultures. They report on this in the journal Nature Communications. In their view, ...

A Varied Life Boosts the Brain’s Functional Networks

Results from a mouse study with novel biosensing technique

17-Jul-2023 - That experiences leave their trace in the connectivity of the brain has been known for a while, but a pioneering study by researchers at the German Center for Neurodegenerative Diseases (DZNE) and TUD Dresden University of Technology now shows how massive these effects really are. The findings in ...