Study reveals new method of preparing imaging agents

Dr. Benjamin Rotstein and collaborators unveil an operationally simple method to prepare carbon isotope-labeled versions of drugs and diagnostics

29-Nov-2022 - Dr. Benjamin Rotstein and collaborators unveil an operationally simple method to prepare carbon isotope-labeled versions of drugs and diagnostics. The development of new pharmaceuticals relies on the ability of scientists to design elegantly specific drugs for targeted clinical trials. And the ...

University of Ottawa's Faculty of Medicine team reveals underpinnings of how motor memory forms

A research team led by Dr. Simon Chen offers new and valuable insights into an enduring mystery of neuroscience

16-Sep-2022 - When you are first learning how to ride a bicycle or play a musical instrument, your physical movements are uncoordinated at best. But with time and lots of repetition, your brain’s motor neurons create a kind of shorthand between mind and muscle. The associated motions eventually become so ...

COVID-19 household transmission is high, with children being a significant source of spread

19-Apr-2022 - A study released today indicates that SARS-CoV-2 (COVID-19) spreads extensively in households, with children being a significant source of that spread. Approximately 50% of household members were infected from the first-infected individual during the study period. Although kids were less likely ...

Cancer-fighting viruses soften up their victims before attacking

Researchers based at the University of Ottawa and The Ottawa Hospital harness virally-programmed extracellular vesicles to shrink tumours in mice

13-Apr-2022 - A research team based at the University of Ottawa and The Ottawa Hospital has developed a virus that infects and kills cancer cells without harming normal cells, while also sending out signals to prepare nearby uninfected cancer cells for viral attack. Their new study, published in Nature ...

New promise in disabling cancer's defences

14-Mar-2017 - Recent study out of the University of Ottawa opens door for new disease therapies in cancer, ALS, Fragile X Syndrome and others. Part of what makes cancer cells so devastating is their ability to fight back against treatments -- sometimes they work, sometimes they don't. But what if we could take ...

How to predict biphasic allergic reactions in children

23-Jun-2015 - Children are more likely to have a repeat, delayed anaphylactic reaction from the same allergic cause, depending on the severity of the initial reaction. The first pediatric study to look at the predictors for this phenomenon was published in Annals of Allergy, Asthma & Immunology.Anaphylaxis is ...

Function found for mysterious heart disease gene

29-Apr-2014 - A new study from researchers at the University of Ottawa Heart Institute (UOHI), published in Cell Reports, sheds light on a mysterious gene that likely influences cardiovascular health. After five years, UOHI researchers now know how one genetic variant works and suspect that it contributes to ...

Ottawa scientists discover new way to enhance stem cells to stimulate muscle regeneration

08-Jun-2009 - Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa have discovered a new way to stimulate muscle regeneration, paving the way for new treatments for debilitating conditions such as muscular dystrophy. The research, to be published in Cell Stem Cell , shows ...

Genetic Research: The New Battleground in the Fight Against Heart Disease

University of Ottawa Heart Institute Leads a New Scientific Focus on Preventive Medicine Aimed at Eliminating Heart Disease

24-Oct-2006 - Modern medicine has the technology and scientific tools to dramatically reduce and probably eliminate heart disease over the next 50 years, says Dr. Robert Roberts, CEO and President of the University of Ottawa Heart Institute (UOHI). Significant research underway at the Heart Institute will soon ...

Genetic Discovery Unlocks Cause of a Common Form of Heart Disease

Heart Institute Research Expected to Fuel New Therapies for Atrial Fibrillation

26-Jun-2006 - Research at the University of Ottawa Heart Institute has revealed that one of the most common forms of heart disease - atrial fibrillation (AF) - is caused by a genetic mutation that occurs during in-utero development. The landmark discovery provides a fresh view of how common diseases may ...