Targeted blocking of inflammatory messenger by tablet for the first time

In a clinical phase 2 study, a research team has demonstrated the effectiveness of an IL-23 blocking treatment against psoriasis, which is administered orally

28-Feb-2024 - A promising approach for the treatment of chronic inflammatory diseases involves modern, targeted therapies that inhibit inflammatory messengers, so-called cytokines, or their signaling pathways, and thus block inflammation without interfering with other processes. As a result, they are usually ...

Smart plaster could accelerate the healing of chronic wounds

International cooperation between materials science and medicine develops gel patches from a 3D printer that can be activated individually

30-Aug-2021 - Circulatory disorders, diabetes or lying in the same position for extended periods can all lead to chronic wounds that do not heal. There are hardly any effective treatment options. A materials science research team from Kiel University (CAU), together with colleagues from the University Medical ...

Large genomic analysis highlights COVID-19 risk factors

An international collaboration uncovers several genetic markers associated with SARS-CoV-2 infection or COVID-19 severity

13-Jul-2021 - In March of 2020, thousands of scientists around the world united to answer a pressing and complex question: what genetic factors influence why some COVID-19 patients develop severe, life-threatening disease requiring hospitalization, while others escape with mild symptoms or none at all? A ...

Sugar leads to early death, but not due to obesity

Study points out that the reduced life expectancy due to sugar consumption could have other causes than previously assumed

24-Mar-2020 - We all know that consuming too much sugar is unhealthy. It increases our risk of developing metabolic disorders, such as obesity and diabetes, and can shorten our life expectancy by several years. It is widely believed that this reduction in lifespan is caused by metabolic defects. However, this ...

Diseases occur when the network of regulatory autoantibodies gets out of balance

Fundamentally new insights into the origin of disease

19-Dec-2018 - Autoantibodies, i.e. antibodies directed against the body's own structures, are usually associated with autoimmune diseases like rheumatism. However, they are in fact a normal part of the immune system in healthy people. There is apparently a network of autoantibodies, which are fine-tuned with ...

Host genome controls skin microbiota and inflammation

19-Sep-2013 - Numerous recent studies linked gut microbiota with various diseases such as obesity of diabetes. Little is known, however, on how gut and skin microbiota composition is controlled. In a recent study published in the journal Nature communications, John Baines, Saleh Ibrahim and their colleagues of ...

Genizon and Institute for Clinical Molecular Biology Replicates Disease Gene Discoveries in Crohn's Disease

Results Confirm the Power of Genizon's Platform and the Quebec Founder Population for Disease Gene Discovery

26-Oct-2005 - Genizon Biosciences and the Institute for Clinical Molecular Biology, University Hospital Schleswig-Holstein announced the replication of many disease gene signals for Crohn's disease, previously discovered by Genizon in the Quebec Founder Population. This replication further confirms the ...