Biochemical mechanism behind a rare, painful genetic disease identified

Study might open door to first effective treatment for ACDC disease

14-Dec-2016 - A team of researchers at the National Institutes of Health has uncovered a possible biochemical mechanism behind a rare, painful genetic disorder called ACDC disease, which causes calcium buildup in the arteries. The finding could lead to the first effective treatment for the potentially ...

Sigma-Aldrich receives National Institutes of Health funding for cardiovascular disease research

Sigma Life Science to Analyze Plasma Samples from Framingham Heart Study in Researching Novel Biomarkers for Cardiovascular Disease

09-Aug-2010 - Sigma-Aldrich® announced it has entered into an agreement with the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, and Boston University (BU) to develop methods to measure several potential biomarkers of atherosclerotic cardiovascular disease (CVD) using ...

New study suggests sickle cell disease may affect brain function in adults

17-May-2010 - Sickle cell disease may affect brain function in adults who have few or mild complications of the inherited blood disease, according to results of the first study to examine cognitive functioning in adults with sickle cell disease. The multicenter study, funded by the National Heart, Lung, and ...

New approach to immune cell analysis seen as first step to better distinguish health and disease

11-Mar-2010 - Investigators have developed a new mathematical approach to analyze molecular data derived from complex mixtures of immune cells. This approach, when combined with well-established techniques, readily identifies changes in small samples of human whole blood, and has the potential to distinguish ...

Blood stem-cell transplant regimen reverses sickle cell disease in adults

15-Dec-2009 - A modified blood adult stem-cell transplant regimen has effectively reversed sickle cell disease in 9 of 10 adults who had been severely affected by the disease, according to results of a National Institutes of Health study in the New England Journal of Medicine. The trial was conducted at the ...