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31 Current news of Friedrich-Alexander-Universität Erlangen-Nürnberg

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Researchers “film” the activation of an important receptor

Study may lead to the development of improved medicines

15-Mar-2024 - An international team of researchers has succeeded in “filming” the activation of an important receptor. They froze the involved molecules at different points in time and photographed them under the electron microscope. They were then able to place these still images in sequence. This sequence ...

asthma Cryogenic electron microscopy drug development +2
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Revolutionary cell therapy: rebooting the immune system stops autoimmune diseases

Single infusion of CAR-T cells replaces immunosuppressive drugs

23-Feb-2024 - In March 2021, doctors at FAU treated a young woman with a severe autoimmune disease with chimeric antigen receptor (CAR) T cells for the first time in the world. Today, almost three years later, they have now been able to publish a pilot study in the New England Journal of Medicine and show that ...

autoimmune diseases B cells B-lymphocytes +6
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Immune cells strengthen bones

New molecular mechanism discovered in inflammatory bone loss

20-Feb-2024 - In osteoporosis, bone mass is lost and bones break more easily. The increased bone loss is either triggered by a hormonal imbalance or as the result of inflammatory diseases such as rheumatoid arthritis or chronic inflammatory bowel diseases. A team of researchers at Department of Medicine 3 – ...

bone diseases bones granulocytes +3
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How antibodies offer protection against an infection with HIV

Team of researchers can explain how HIV antibodies work

16-Oct-2023 - How do antibodies prevent an infection with HIV? This is a question that a team of researchers led by Prof. Dr. Klaus Überla from the Institute of Clinical and Molecular Virology at Universitätsklinikum Erlangen and Dr. Christiane Stahl-Hennig from the German Primate Center in Göttingen can now ...

antibodies HIV
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Does dirt not protect against allergies after all?

New study raises doubts about hygiene hypothesis

12-Oct-2023 - Does playing in dirt really make children healthier and protect against allergies? The new study conducted by a team of researchers at FAU and the Karolinska Institutet in Stockholm has now raised doubts about this assumption. The researchers have published their findings in the research magazine ...

allergies asthma autoimmune diseases +3
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Pills printed with the 3D printer

Production of personalized medication through 3D printing

10-Oct-2023 - Almost a third of the population in Germany needs to take medication on a daily basis. One in four of these people regularly takes three or more different types of medication at the same time. Various pills pile up in these patients’ pill dispensers for various days of the week. The correct ...

3D printing drug manufacturing
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Fintetuning for antibodies

The strength of the immune reaction triggered by antibodies can be regulated

11-Jul-2023 - Antibodies are crucial, not only for treating tumors and infections. Sometimes, however, the immune reaction they trigger can be too strong and end up causing more damage, for example in the case of people infected with Covid-19. Problems such as these can often be avoided by finetuning ...

antibodies immune system immunoglobulin G
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Putting an end to rheumatoid arthritis?

Interdisciplinary research team unlocks the mechanism for inhibiting inflammation of the joints

12-May-2023 - Immunoglobulin G antibodies (IgG) play an important role as drivers of inflammation in infectious diseases and autoimmune diseases. However, if the same immunoglobulin antibodies from the blood plasma of healthy donors are cleansed and injected into a patient’s bloodstream, they exhibit ...

antibodies IgG antibodies immunoglobulins +1
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How vitamin D3 helps allergic asthma

Researchers discover how the vitamin has a positive effect on the immune response

26-Apr-2023 - A vitamin D3 deficiency can lead to severe symptoms, for example in people suffering from allergic asthma. This has already been shown in several studies. However, we still do not fully understand how exactly this vitamin influences the cellular inflammatory reaction in the body. A team of ...

allergic asthma vitamin D vitamins
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Creating an artificial pathologist

Researchers have created a new method to analyze cells in tissue samples from cancer patients using artificial intelligence

14-Apr-2023 - A team from the Max Planck Institute for the Science of Light (MPL) and FAU has created a new, fast and precise method for clinicians to analyse cells in tissue samples from cancer patients without the need for a trained pathologist. They use artificial intelligence to evaluate the data their ...

artificial intelligence biopsies cancer +4