Storing defective energy: How the aging brain remains efficient

New insights into healthy brain aging

06-Feb-2026 - In a recent study published in Cell Systems, an international research team led by Dr. Dennis de Bakker from the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena and Prof. Robert W. Williams from the University of Tennessee Health Science Center, Memphis, USA, studied how ...

Cancer cells have an Achilles heel

"This basic research can form the basis for new therapeutic strategies against cancer"

28-May-2025 - A hidden weak point in tumor cells opens up a new starting point for cancer drugs: a research team from Saarland University and the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) targeted a key protein as part of an international project: it offers a target for sensitively ...

Interaction between metabolic health and healthy aging supported

“It was very exciting for us to discover a longevity intervention that is effective in late life"

15-Mar-2024 - New findings on the role of RNA Polymerase I in longevity and metabolic health - excessive protein synthesis shortens lifespan - connection between energy metabolism and cancer risk. Ribosomes, the "translation factories" of the cell, are cellular organelles that play a central role in protein ...

Study identifies multi-organ response to seven days without food

"For the first time, we’re able to see what’s happening on a molecular level across the body when we fast"

05-Mar-2024 - New findings reveal that the body undergoes significant, systematic changes across multiple organs during prolonged periods of fasting. The results demonstrate evidence of health benefits beyond weight loss, but also show that any potentially health-altering changes appear to occur only after ...

Influence of cell phone radiation on food intake proven

Scientists at the University of Lübeck uncover influence of cell phone radiation on brain metabolism and food intake

05-Apr-2022 - Cell phones have become an indispensable part of modern life. For children and adolescents in particular, the increased use of the popular communication and play device can be problematic on several levels. The radiation emitted by cell phones is absorbed to a large extent by the head and can ...

Paradigm shift: Methanogenic microbes not always limited to methane

"It is quite something to overturn such an old paradigm, namely that all methanogens are obligate methanogenic"

14-Jan-2022 - A study led by microbiologists at TU Dresden shows that methanogenic archaea do not always need to form methane to survive. It is possible to bypass methanogenesis with the seemingly simpler and more environmentally friendly acetogenic energy metabolism. These new findings provide evidence that ...

Deciphering how the brain controls our weight

Jens Brüning receives 2019 Heinrich Wieland Prize

12-Nov-2019 - Professor Jens Brüning, Director at the Max Planck Institute for Metabolism Research in Cologne, Germany, has been honoured with the 2019 Heinrich Wieland Prize for his pioneering work on how the brain regulates the uptake, storage, and use of energy in the body. He has shown that certain brain ...

Do chemicals make you fat?

The EU research project EDCMET is investigating the effect of endocrine disruptors on metabolism

28-Jan-2019 - January 2019 saw the launch of the EU research project EDCMET, in which scientists from the German Federal Institute for Risk Assessment (BfR) are also involved. EDCMET stands for "Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome path-ways" and is ...

Our circadian clock sets the rhythm for our cells’ powerhouses

07-Mar-2018 - Cellular energy metabolism also follows the rhythm of the circadian clock. A University of Basel study has now shown exactly how this works by revealing the relationship between the circadian rhythm and the mitochondrial network for the first time. Countless genetically controlled clocks tick ...

Tom22, the bouncer of the mitochondrion

Freiburg researcher discovers three signalling pathways that regulate the gates to the powerhouses of the cell

07-Oct-2013 - Mitochondria burn sugar and supply the cell with energy. They were long thought to be structures that are relatively independent of the cell. However, Carolin Gerbeth, a PhD student from the trinational research training group “Membrane Proteins and Biological Membranes,” has now identified no ...