Promega and Watchmaker Genomics Announce Strategic Partnership

Partnership to Advance Molecular Analysis with Next-Generation Reverse Transcriptase

15-Sep-2025
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Promega Corporation has entered a strategic partnership with Watchmaker genomics to license a novel engineered reverse transcriptase. Designed for enhanced accuracy and sensitivity in RNA Analysis, the enzyme will enhance Promega capabilities to manufacture and deliver both catalog and customized solutions for clinical, applied and pharmaceutical molecular applications.

"Watchmaker’s enzyme offers a combination of attributes that establish a new benchmark for reverse transcriptase performance," says Sara Mann, VP of Commercial Excellence at Promega. "By incorporating it into our portfolio, we are giving customers a powerful tool for improved accuracy and enhanced sensitivity of RNA-based assays."

This partnership marks the beginning of an expanded collaboration between Watchmaker Genomics and Promega, with both companies committed to developing next-generation enzyme technologies that address the evolving needs of molecular diagnostics and life science research.

Engineered for Clinical and Research Precision

Developed with Watchmaker’s proprietary protein engineering platform, the reverse transcriptase reflects the same precision design principles that underpin Watchmaker’s next-generation sequencing (NGS) reagent portfolio and delivers performance advantages that set it apart in advancing molecular analysis applications.

"This enzyme will meaningfully improve the accuracy and reliability of RNA analysis in diagnostic and research labs," said Brian Kudlow, Chief Scientific Officer of Watchmaker Genomics. "This collaboration showcases the power of our enzyme engineering platform to deliver specialized genomics solutions."

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