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Small infections can be fatal: Millions of people die each year from sepsis, an overreaction of the immune system. A new immune signaling molecule, designed by a research team from the Technical University of Munich (TUM), now provides the basis for potential new approaches in sepsis therapy. The nu more
The long known gut hormone secretin has a newly discovered, additional function: It activates thermogenesis in brown fat, which triggers saturation. Scientists of the Technical University of Munich (TUM) in collaboration with an international team have succeeded in this important step. Only a few w more
Russian researchers from Prokhorov General Physics Institute of the Russian Academy of Sciences (GPI RAS) and the Moscow Institute of Physics and Technology (MIPT) have developed the world’s first ultrasensitive method for rapid detection of small molecules. This method detects trace amounts of toxi more
It’s supposed to help keep your body healthy in stressful situations. But the constant stress of our everyday lives means we’re getting overexposed to cortisol. Raychelle Burks, Ph.D. explains why too much cortisol is bad for you in the latest episode of the Reactions series "Get To Know A Molec ... more
By amending methodology to utilize eVol® for sample preparation processes for GC-C-IRMS C isotope ratio analysis, the ISORA department has: improved sample preparation conditions and the GC-C-IRMS analysis results by removing the risk of ghost peaks, more
Detecting homo-FRET-FP of mCherry labelled insulin with the PHERAstar allows for monitoring of cellular insulin-granules in 384 well plate format more
Adrenaline Adrenaline, also known as epinephrine, is a hormone produced in high stress or exciting situations. Noradrenaline Noradrenaline, also known as norepinephrine, is a neurotransmitter that affects attention & and responding actions in the brain. Dopamine Dopamine is associated with feelings more
Insect venoms are complicated. Really complicated. You could be forgiven for thinking that it must be a relatively simple company of chemicals that makes up the painful sensation of a bee or wasp sting, but in fact a hugely complex mixture of all sorts of compounds – proteins, peptides, enzymes, and more
After yesterday’s new year celebrations, you might well be nursing a sore head this morning after a few drinks too many. This is a chemical consequence of consuming alcoholic beverages, but it’s one that, surprisingly, we still don’t fully understand. There are, however, a number of chemical suspect more
by Jiaxing Zhang, Yi Liang, Yuan Ai, Xiaosi Li, Juan Xie, Youping Li, Wenyi Zheng, Rui He Purpose In absence of direct comparison randomized controlled trials (RCTs), indirect comparison was conducted to evaluate the efficacy and safety of thrombopoietin-receptor agonists (TPO-RAs) in treatment o more
by Rafael Rios, Carmen Pineda, Ignacio Lopez, Juan Muñoz-Castañeda, Mariano Rodriguez, Escolastico Aguilera-Tejero, Ana I. Raya This study was designed to evaluate the influence of phosphorus (P) restriction on the deleterious effects of high fat diets on mineral metabolism. Twenty-four rats were more
by Xiaozhen Yao, Lei Tian, Jun Yang, Yan-Na Zhao, Ying-Xiu Zhu, Xinhua Dai, Yunde Zhao, Zhong-Nan Yang Gametophytic development in Arabidopsis depends on nutrients and cell wall materials from sporophytic cells. However, it is not clear whether hormones and signaling molecules from sporophytic ti more
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