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Thyroxine, or 3,5,3',5'-tetraiodothyronine (often abbreviated as T4), a form of thyroid hormones is the major hormone secreted by the follicular cells of the thyroid gland.
Additional recommended knowledge
T4 is transported in blood, with 99.95% of the secreted T4 being protein bound, principally to thyroxine-binding globulin (TBG), and, to a lesser extent, to transthyretin and serum albumin.
T4 is involved in controlling the rate of metabolic processes in the body and influencing physical development.
Note: Thyroxine is a prohormone and a reservoir for the active thyroid hormone triiodothyronine (T3).
T4 is converted in the tissues by deiodinases to T3.
The "D" isomer is called "Dextrothyroxine" and is used as a lipid modifying agent.
The half-life of thyroxine once released into the blood circulatory system is about 1 week
Categories: Thyroid hormones | Iodinated tyrosine derivatives
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Thyroxine". A list of authors is available in Wikipedia.|