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Swainsonine is a potent inhibitor of Golgi alpha-mannosidase II, immunomodulator and potential anticancer agent. Disruption of Golgi alpha-mannosidase II with swainsonine induces hybrid-type glycans. These glycans have a Man5GlcNAc2 core with processing on the 3-arm that resembles so-called complex-type glycans.
Additional recommended knowledge
The pharmacological properties of this product have not been fully investigated.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Swainsonine". A list of authors is available in Wikipedia.|