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Protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization.
Additional recommended knowledge
When mixed with insulin, protamines slow down the onset and increase the duration of insulin action (see NPH insulin).
Protamine sulfate is an antidote for heparin.
Mice, humans, and certain fish have 2 or more different protamines, whereas the sperm of bull, boar, rat, rabbit, guinea pig, and ram have one form of protamine.
The 2 human protamines are denoted PRM1 and PRM2.
Examples of protamines from fish are:
Categories: Genes on chromosome 16 | Proteins
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Protamine". A list of authors is available in Wikipedia.|