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Postweaning multisystemic wasting syndrome
Postweaning multisystemic wasting syndrome ("PMWS") is a porcine disease. This disease causes illness in piglets, with clinical signs including progressive loss of body condition, visibly enlarged lymph nodes, difficulty in breathing, and sometimes diarrhea, pale skin, and jaundice. PMWS has been reported from most pig-producing countries of the world at huge cost to agriculture. PMWS is caused by porcine circovirus type 2 (PCV2)
Additional recommended knowledge
PMWS & PCV2
PMWS is associated with infection of pigs by porcine circovirus type 2 (PCV2). However, the exact relationship between PCV2 infection and PMWS remains unclear. There is not a straightforward relationship between infection and disease. PCV2 has a near universal distribution – present in most pig herds. In contrast, PMWS is more sporadic in its distribution. Experimental induction of PMWS has not been achieved by PCV2 infection alone, using infectious DNA clones of the virus or a pure form of PCV2 derived from infectious DNA clones. Therefore it is assumed that PMWS is a multifactorial disease. PCV-2 is necessary but not sufficient for the development of PMWS. There is no significant correlation of the disease with virus sequence variation with affected and control pigs.
Both PMWS and PDNS (Porcine Dermatitis and Nephropathy Syndrome) are associated to PCV2. It seems that many pigs affected by the circovirus also tend to develop secondary bacterial infections, like Glässer disease (Haemophilus parasuis), Pulmonary Pasteurellosis, Colibacilosis and Salmonellosis and others. Dissected morbid pigs showed lesions in multiple organs, especially in lymphoid tissues, giving birth to the term "multisystemic".
"The distinguishing lesion caused by PCV2 is an inflammatory infiltration by histocite cells with variable intensity, located in the lymphoid organs, liver, kidney, and lung"
Wasting pigs is the most common sign of PMWS infection, increasing the mortality rate significantly.
Management practices to decrease severity of PMWS
François Madec, a French author, has written many recommendations on how reduce PMWS symptoms. They are mostly measures for disinfection, management, and hygiene, referred to as the "20 Madec Points" [Madec & Waddilove, 2002].
These measures have recently been expanded upon by Dr. David Barcellos, a professor at the Veterinary College in the Universidade Federal do Rio Grande do Sul, Rio Grande do Sul, Brazil. He presented these points at "1st Universidade Federal do Rio Grande do Sul Symposium about swine management, reproduction, and hygiene".
He divided his points by pig growth stage, and they can be loosely summarized as:
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Postweaning_multisystemic_wasting_syndrome". A list of authors is available in Wikipedia.|