Pachydermoperiostosis

Pachydermoperiostosis (PDP) is a rare disorder characterized by clubbing of the fingers, thickening of the skin of the face (pachyderma) and excessive sweating (hyperhidrosis). It was first described in 1868. However it wasn't until 1935, when Touraine-Solente-Golé recognised it as a syndrome.

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In fact, there are 3 forms: 1. a complete form (pachydermia and periostosis), 2. an incomplete form (without pachydermia), and 3. a forme fruste (pachydermia with minimal-to-absent skeletal changes).