| IUPAC name
|| 2-(2-oxopyrrolidin-1-yl) butanamide
| CAS number
| ATC code
| Molecular formula
| Molar mass
|| 170.21 g mol-1
|| Fine white crystalline powder
| Routes of|
| Oral, Intravenous
| 6 - 8 hr
| Legal status
| Except where noted otherwise, data are given for|
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references
Levetiracetam (INN) (pronounced /lɛvɨtɪˈræsɨtæm/) is an anticonvulsant medication used to treat epilepsy. It is S- enantiomer of etiracetam, structurally similar to the prototypical nootropic drug piracetam. Along with other anticonvulsants like gabapentin, it is also sometimes used to treat neuropathic pain. Levetiracetam is marketed under the trade name Keppra. Keppra is manufactured by UCB Pharmaceuticals Inc.
Additional recommended knowledge
Levetiracetam has recently been approved in the United Kingdom as a monotherapy treatment for epilepsy. It is also used in veterinary medicine for similar purposes.
Side effects include: ataxia (sudden loss of balance); hair loss; pins and needles sensation in the extremities; psychiatric symptoms ranging from irritability to depression; and other common side effects like headache and nausea.
Recent literature (and paper 2.163 in ) suggests that the addition of pyridoxine (vitamin B6) may curtail some of the psychiatric symptoms.
- Keppra (levetiracetam) Final Printed Label New and Generic Drug Approvals. 29 Dec 1999. Center for Drug Evaluation and Research, U.S. Food and Drug Administration. Accessed 31 August 2005.
- SID 7847774 -- PubChem Substance Summary. The PubChem Project. National Center for Biotechnology Information. Retrieved on 7 December, 2005.
|Aniracetam • Brivaracetam • Coluracetam • Etiracetam • Fasoracetam • Levetiracetam • Nebracetam • Nefiracetam • Oxiracetam • Phenylpiracetam • Piracetam • Pramiracetam • Rolziracetam • Seletracetam|
|Barbiturates||Barbexaclone, Metharbital, Methylphenobarbital, Pentobarbital, Phenobarbital, Primidone|
|Hydantoins||Ethotoin, Fosphenytoin, Mephenytoin, Phenytoin|
|Oxazolidinediones||Ethadione, Paramethadione, Trimethadione|
|Succinimides||Ethosuximide, Mesuximide, Phensuximide|
|Benzodiazepines||Clobazam, Clonazepam, Clorazepate, Diazepam, Lorazepam, Midazolam, Nitrazepam, Temazepam|
|Carboxamides||Carbamazepine, Oxcarbazepine, Rufinamide|
|Fatty acid derivatives||Valpromide, Valnoctamide|
|Carboxylic acids||Valproic acid (Sodium valproate & Valproate semisodium), Tiagabine|
|Others||GABA analogs: Gabapentin, Pregabalin, Progabide, Vigabatrin -- Monosaccharides: Topiramate -- Aromatic allylic alcohols: Stiripentol -- Ureas: Phenacemide, Pheneturide -- Phenyltriazines: Lamotrigine
Carbamates: Emylcamate, Felbamate, Meprobamate -- Pyrrolidines: Brivaracetam, Levetiracetam, Nefiracetam, Seletracetam
Sulfa drugs: Acetazolamide, Ethoxzolamide, Sultiame, Zonisamide -- Propionates: Beclamide -- Aldehydes: Paraldehyde -- Bromides: Potassium bromide, Sodium bromide