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Gallamine (as gallamine triethiodide) is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release.
Additional recommended knowledge
Gallamine is commonly used to stabilize muscle contractions during surgical procedures.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Gallamine". A list of authors is available in Wikipedia.|