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Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. It is adapted from cysteamine, pantothenate, and adenosine triphosphate.
Additional recommended knowledge
Coenzyme A is synthesized in a five-step process from pantothenate:
Since coenzyme A is chemically a thiol, it can react with carboxylic acids to form thioesters, thus functioning as an acyl group carrier. It assists in transferring fatty acids from the cytoplasm to mitochondria. A molecule of coenzyme A carrying an acetyl group is also referred to as acetyl-CoA. When it is not attached to an acyl group it is usually referred to as 'CoASH' or 'HSCoA'.
List of coenzyme A activated acyl groups
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Coenzyme_A". A list of authors is available in Wikipedia.|