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Additional recommended knowledge
Separating serum proteins by electrophoresis is a valuable diagnostic tool as well as a way to monitor clinical progress.
Types of blood proteins:
All the plasma proteins are synthesized in liver except gamma globulins. Globulins are of three types- alpha,beta and gamma.
Other types of blood proteins include:
60% of plasma proteins are made up of the protein albumin, which are major contributors to osmotic pressure of plasma which assists in the transport of lipids and steroid hormones. Globulins make up 35% of plasma proteins and are used in the transport of ions, hormones and lipids assisting in immune function. 4% is fibrinogen and this is essential in the clotting of blood and can be converted into insoluble fibrin. Regulatory proteins which make up less than 1% of plasma proteins are proteins such as enzymes, proenzymes and hormones. Current research regarding blood plasma proteins is centered on performing proteomics analyses of serum/plasma in the search for biomarkers. These efforts started with two-dimensional gel electrophoresis efforts in the 1970s and in more recent times this research has been performed using LC-tandem MS based proteomics.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Blood_proteins". A list of authors is available in Wikipedia.|