Classification & external resources
Berylliosis or chronic beryllium disorder (CBD) is an occupational lung disease. It is a chronic allergic-type lung response and chronic lung disease caused by exposure to beryllium and its compounds. The condition is incurable but symptoms can be treated.
Additional recommended knowledge
With single or prolonged exposure by inhalation, the lungs become hypersensitive to beryllium causing the development of small inflammatory nodules, called granulomas.
Granulomas are seen in other chronic diseases, such as tuberculosis and sarcoidosis, and it can occasionally be hard to distinguish berylliosis from these disorders.
Ultimately, this process leads to restrictive lung disease, a decreased diffusion capacity.
Clinically patients experience cough and shortness of breath. Other symptoms include chest pain, joint aches, weight loss and fever.
Rarely, one can get granulomas in other organs including the liver.
The onset of symptoms can range from weeks up to tens of years from the initial exposure. In some individuals a single exposure can cause berylliosis.
|Pathology of respiratory system (J, 460–519)|
|Acute upper respiratory infections||Upper respiratory tract infection · Common cold · Rhinitis · Sinusitis · Pharyngitis (Strep throat) · Tonsillitis · Laryngitis · Tracheitis · Croup · Epiglottitis|
|Influenza and Pneumonia||Influenza · Pneumonia (Viral, Bacterial, Bronchopneumonia) · Severe acute respiratory syndrome|
|Other acute lower respiratory infections||Bronchitis (Acute, Chronic) · Bronchiolitis|
|Other diseases of upper respiratory tract||Vasomotor rhinitis · Hay fever · Atrophic rhinitis · Nasal polyp · Deviated septum · Adenoid hypertrophy · Peritonsillar abscess · Vocal fold nodule · Laryngospasm|
|Chronic lower respiratory diseases||Emphysema · COPD · Asthma · Status asthmaticus · Bronchiectasis|
|Lung diseases due to external agents||Pneumoconiosis (Coalworker's pneumoconiosis, Asbestosis, Silicosis, Bauxite fibrosis, Berylliosis, Siderosis) · Byssinosis · Hypersensitivity pneumonitis (Farmer's lung, Bird fancier's lung)|
|Other, principally affecting|
|Acute respiratory distress syndrome · Pulmonary edema · Hamman-Rich syndrome · Interstitial lung disease|
|Suppurative and necrotic conditions|
of lower respiratory tract
|Lung abscess · Pleural effusion · Empyema|
|Other||Pneumothorax · Hemothorax · Hemopneumothorax · Mendelson's syndrome · Respiratory failure · Atelectasis · Mediastinal emphysema · Mediastinitis|
|see also congenital (Q30–Q34, 748)|