Beckman Coulter GmbH

Adapting the Power of Density Gradient Separations for Gene Therapy Analytics

Adapting the Power of Density Gradient Separations for Gene Therapy Analytics

DGE-AUC is a versatile, thermodynamics driven analytical method based on well known foundational understanding of CsCl density gradients

Overcoming the Hurdles of DGUC for Optimized Gene Therapy Purification Workflows

Overcoming the Hurdles of DGUC for Optimized Gene Therapy Purification Workflows

Density Gradient Ultracentrifugation (DGUC) is a centrifuge-based technique for providing superior purification of viral vectors (e.g., isolating full AAV particles from partial and empty capsids), along with other materials (such as plasmid DNA ...

An Intro to Characterization of Biomolecules Using Analytical Ultracentrifugation

An Intro to Characterization of Biomolecules Using Analytical Ultracentrifugation

In this webinar we will start with the principles of analytical ultracentrifugation and take a tour through the technology behind AUC, including UV/Vis absorbance mode and interference mode signal detection, and look at experiment design and ...

Characterizing Viral Vector Fullness in Density Gradient Separations

Characterizing Viral Vector Fullness in Density Gradient Separations

Density gradient equilibrium AUC (DGE-AUC) is a highly simplified analytical method that provides the same high-resolution benefits as its prep-scale counterpart, along with numerous advantages over the current gold standard sedimentation ...