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BromMarin is a spin-off from Technische Universität Bergakademie Freiberg in Germany with the aim of developing novel methods in marine biotechnology. We extract marine sponges of the Verongida order in a way that not just the extraction of bromotyrosines, but simultaneously the isolation of sponge scaffolds becomes possible. The bromotyrosines are applied as anti-cancer agent or as antibiotics in pharmacy and cosmetics. The sponge scaffold are needed as filter material in material science, as a natural wound healer in biomedicine or as host for stem cells and chondrocytes in Tissue Engineering. A pilot sponge farming plant in the Mediterranean ensures the sustainable and abundant production of marine agents. Like in muscle or fish farming plants, marine sponges are grown, harvested and processed for the first time. At the moment we focus on culturing the “gold sponge” Aplysina aerophoba. Further sponge species are consecutively investigated. Within the laboratory, the sponge tissue is processed further. After the extraction and purification of the bromotyrosines, the highest possible purity (>99%) is confirmed externally by cooperation partners. Every sample is investigated before the delivery to guarantee the purity.
We strive to make the mechanisms, which made sponges survive for millions of years, applicable to mankind.
Marine sponges represent rather simple organisms and although they exist since millions of years, their survival strategy is not yet decoded. However, what researchers have recognized are the manifold effects of the chemical defense of marine sponges. Building upon, BromMarin strives to squeeze the sponge’s full potential. Always oriented on state-of-the-art research, applications for pharmacy are included as well as for cosmetics, material sciences and biomedicine.
Bromotyrosines and other marine agents are provided in quantities that are required for clinical trials.
Through a pilot sponge farming plant, BromMarin is able to extract agents from sponges in a sustainable manner and thereby to begin a new chapter in marine pharmacy.
Innovations in processes and products
An innovative extraction process enables not just the extraction of bromotyrosines, but simultaneously the isolation of sponge scaffolds. The potential of the α-Chitin sponge scaffolds is manifold and BromMarin now empowers research to develop it. Due to the increased yield of bromotyrosines from the sponge, marine agents can be provided, which have previously not been available on the market.