Breast Cancer

Aggressive forms of breast cancer often manipulate the immune response in their favor. This manipulation is revealed in humans by the same immunological "signature" as in mice. This is shown by a study carried out by scientists from the University of Bonn together with Dutch colleagues. Their method more

Stem cells of the teeth can contribute to the regeneration of non-dental organs, namely mammary glands. According to a new study from researchers at the University of Zurich, dental epithelial stem cells from mice can generate mammary ducts and even milk-producing cells when transplanted into mammar more

Herceptin was the first monoclonal antibody that blocks a cancer causing protein. For the invention of Herceptin and the development of a life-saving therapy for women with breast cancer, three researchers are now receiving the Lasker~DeBakey Clinical Medical Research Award: Axel Ullrich, Emeritus D more

Transfection is a method for delivering nucleic acids, either DNA or RNA, into animal cells in vitro. In applications such as protein production, the main purpose is to produce protein; consequently any effects on endogenous gene expression are gener more

High Resolution Melting (HRM) is a novel and promising screening technique used for mutation analysis and detection. Its application prevents the need to sequence all the exons of a gene when looking for novel mutations. The method is therefore time- more

by Monika Lesicka, Ewa Jabłońska, Edyta Wieczorek, Barbara Seroczyńska, Anna Siekierzycka, Jarosław Skokowski, Leszek Kalinowski, Wojciech Wąsowicz, Edyta Reszka Breast cancer has a multifactorial etiology. One of the supposed and novel mechanisms is an alteration of circadian gene expression. Ci more

The adult mammary gland is a bilayered branching epithelial structure consisting of an outer layer of basal cells and an inner layer of luminal cells. The neonatal structure expands rapidly during puberty and then undergoes cyclic growth in response to the changing hormonal stimuli (progesterone and more

Marine Drugs, Vol. 16, Pages 220: Cyanopeptolins with Trypsin and Chymotrypsin Inhibitory Activity from the Cyanobacterium Nostoc edaphicum CCNP1411 Marine Drugs doi: 10.3390/md16070220 Authors: Hanna Mazur-Marzec Anna Fidor Marta Cegłowska Ewa Wieczerzak Magdalena Kropidłowska Ma more