Topic human antibodies

Products human antibodies

ELISA kits for the measurment of SDF-1/CXCL12

SDF-1α (CXCL12) is a CXC chemokine. The small basic protein (ca. 8 kDa) has no glycosylation site in its sequence. The homology properties of SDF-1α are unique among the chemokines more

News human antibodies

• arGEN-X advances third therapeutic antibody program into preclinical development

  arGEN-X announced that it has progressed ARGX-111, its third therapeutic candidate, into formal preclinical development.ARGX-111 is a novel, fully human antibody specific for c-Met, a receptor tyrosine kinase involved in cell proliferation, angiogenesis and metastasis. c-Met is widely implicated in more

• MorphoSys Strengthens Patent Position on MOR202 Program

  MorphoSys AG announced that the US Patent and Trademark Office (USPTO) has granted a patent covering the Company's cancer compound MOR202. The new patent (US 8,088,896) covers MorphoSys's HuCAL antibody against CD38 as well as pharmaceutical compositions comprising the same, and has a scheduled expi more

• Genmab announces progress with Lundbeck collaboration

  Genmab A/S announced it had reached the first pre-clinical milestone in the collaboration with H. Lundbeck A/S, triggering a €1 million payment. Genmab has reached the first milestone in the collaboration with H. Lundbeck A/S to create and develop human antibody therapeutics for disorders of the cen more

Publications human antibodies

• Phage‐derived fully human antibody scFv fragment directed against human vascular endothelial growth factor receptor 2 blocked its interaction with VEGF

  Abstract Vascular endothelial growth factor receptor 2 (VEGFR‐2) plays a critical role in tumor angiogenesis. None therapeutic antibodies targeting VEGFR‐2 are available in clinical use. Herein, we describe the screening of a new single‐chain antibody fragment (scFv) targeting extracellular domai more

• Mouse model recapitulating human Fc{gamma} receptor structural and functional diversity [Immunology]

  The in vivo biological activities of IgG antibodies result from their bifunctional nature, in which antigen recognition by the Fab is coupled to the effector and immunomodulatory diversity found in the Fc domain. This diversity, resulting from both amino acid and glycan heterogeneity, is translated more

• Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus

  Increasing evidences suggest that the type I interferon α (IFNα) plays a critical role in the etiopathogenesis of systemic lupus erythematosus (SLE), which makes it a promising therapeutic target for the treatment of the disease. By screening a large size non-immune human antibody library, we have d more

Market studies human antibodies

• H1N1 (Swine Influenza) - Pipeline Assessment and Market Forecasts to 2017

  Introduction GlobalData, the industry analysis specialist, has released its new report, “H1N1 (Swine Influenza) - Pipeline Assessment and Market Forecasts to 2017”. The report is an essential source of information and analysis on the global H1N1 (Swine Influenza) Therapeutics market. The report ide more

• Affitech A/S (AFFITECH) - Financial and Strategic SWOT Analysis Review

  Affitech A/S (Affitech) is a publicly held pharmaceutical company engaged in the discovery and development of human antibody therapeutics in cancer and other diseases of unmet medical need. The product pipeline of the company which are in various phases of development includes at001, at003, at004, a more

• Tularik, Inc. (TLRK) - Strategic SWOT Analysis Review

  Tularik, Inc. (Tularik) is a pharmaceutical company that is engaged in the discovery and development of oral medicines. The products offered by the company act through the regulation of gene expression. The company is focused on the development of drugs for the treatment of esophageal cancer, gastri more

Websites human antibodies