Human Antibodies

Products Human Antibodies

ELISA kits for the measurment of SDF-1/CXCL12

SDF-1α (CXCL12) is a CXC chemokine. The small basic protein (ca. 8 kDa) has no glycosylation site in its sequence. The homology properties of SDF-1α are unique among the chemokines more

News Human Antibodies

• arGEN-X advances third therapeutic antibody program into preclinical development

  arGEN-X announced that it has progressed ARGX-111, its third therapeutic candidate, into formal preclinical development.ARGX-111 is a novel, fully human antibody specific for c-Met, a receptor tyrosine kinase involved in cell proliferation, angiogenesis and metastasis. c-Met is widely implicated in more

• MorphoSys Strengthens Patent Position on MOR202 Program

  MorphoSys AG announced that the US Patent and Trademark Office (USPTO) has granted a patent covering the Company's cancer compound MOR202. The new patent (US 8,088,896) covers MorphoSys's HuCAL antibody against CD38 as well as pharmaceutical compositions comprising the same, and has a scheduled expi more

• Genmab announces progress with Lundbeck collaboration

  Genmab A/S announced it had reached the first pre-clinical milestone in the collaboration with H. Lundbeck A/S, triggering a €1 million payment. Genmab has reached the first milestone in the collaboration with H. Lundbeck A/S to create and develop human antibody therapeutics for disorders of the cen more

Publications Human Antibodies

• Affinity Maturation and Fine Functional Mapping of an Antibody Fragment against a Novel Neutralizing Epitope on Human Vascular Endothelial Growth Factor

  We have previously reported the isolation of a novel single-chain variable fragment (scFv) against vascular endothelial growth factor (VEGF), from a phage-displayed human antibody repertoire. This scFv, denominated 2H1, was shown to block the binding of VEGF to its receptor but exhibited a moderate more

• Effect of glycosylation on the partition behavior of a human antibody in aqueous two‐phase systems

  Human proteins are expressed in some hosts wrongly glycosylated or nonglycosylated. Although it is accepted that glycosylation contributes to the stability of the protein in solution, the effect of glycosylation on the stability of human antibodies is not fully understood. In this work, we present more

• Evasion of killing by human antibody and complement through multiple variations in the surface oligosaccharide of Haemophilus influenzae

  Summary The lipopolysaccharide (LPS) of H. influenzae is highly variable. Much of the structural diversity is derived from phase variation, or high frequency on‐off switching, of molecules attached during LPS biosynthesis. In this study, we examined the dynamics of LPS phase variation following more

Market studies Human Antibodies

• H1N1 (Swine Influenza) - Pipeline Assessment and Market Forecasts to 2017

  Introduction GlobalData, the industry analysis specialist, has released its new report, “H1N1 (Swine Influenza) - Pipeline Assessment and Market Forecasts to 2017”. The report is an essential source of information and analysis on the global H1N1 (Swine Influenza) Therapeutics market. The report ide more

• Affitech A/S (AFFITECH) - Financial and Strategic SWOT Analysis Review

  Affitech A/S (Affitech) is a publicly held pharmaceutical company engaged in the discovery and development of human antibody therapeutics in cancer and other diseases of unmet medical need. The product pipeline of the company which are in various phases of development includes at001, at003, at004, a more

• Tularik, Inc. (TLRK) - Strategic SWOT Analysis Review

  Tularik, Inc. (Tularik) is a pharmaceutical company that is engaged in the discovery and development of oral medicines. The products offered by the company act through the regulation of gene expression. The company is focused on the development of drugs for the treatment of esophageal cancer, gastri more

Websites Human Antibodies