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Hitachimycin, also known as stubomycin, is a cyclic polypeptide produced by Streptomyces that acts as an antibiotic. It exhibits cytotoxic activity against mammalian cells, Gram-positive bacteria, yeast, and fungi, as well as hemolytic activity; this is mediated by changes at the cell membrane and subsequent lysis. Owing to its cytotoxic activity against mammalian cells and tumors, it was first proposed as a antitumor antibiotic.
As of 2007, it has not been used in a clinical setting.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hitachimycin". A list of authors is available in Wikipedia.|