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The zebrafish is a master of regeneration: If brain cells are lost due to injury or disease, it can simply reproduce them - contrary to humans where this only happens in the fetal stage. However, the zebrafish is evolutionarily related to humans and, thus, possesses the same brain cell types as huma more
It is already known that zebrafish can flexibly regenerate their hearts after injury. An international research group led by Prof. Nadia Mercader of the University of Bern now shows that certain heart muscle cells play a central role in this process. The insights gained could be used to initiate a s more
If zebrafish larvae used the internet, they might soon be able to download a map of their entire brain. "We're not at that point yet", explains Michael Kunst from the Max Planck Institute of Neurobiology. "Nevertheless, our first atlas detailing over 2,000 neurons is now available online." As such, more
Molecular prosthetics are small molecules that can replace missing proteins to treat diseases. Illinois professor Martin Burke describes one that could treat anemia by replacing an iron transport protein. more
As developmental and cell biologist Valentina Greco stood on a stage in Philadelphia last December, candid time-lapse shots of some of the body’s most elusive cells flashed behind her in quick succession. These stem cells, photographed in a living mouse , were caught in the acts of dividing, differe more
Viruses, Vol. 10, Pages 316: Non-Primate Lentiviral Vectors and Their Applications in Gene Therapy for Ocular Disorders Viruses doi: 10.3390/v10060316 Authors: Vincenzo Cavalieri Elena Baiamonte Melania Lo Iacono Lentiviruses have a number of molecular features in common, starting more
by Felix Ellett, Vahid Pazhakh, Luke Pase, Erica L. Benard, Harshini Weerasinghe, Denis Azabdaftari, Sultan Alasmari, Alex Andrianopoulos, Graham J. Lieschke Neutrophils and macrophages provide the first line of cellular defence against pathogens once physical barriers are breached, but can play more
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