Viral Infection

A large number of viruses are known to make life difficult for both humans and animals. While broad-spectrum antibiotics can offer protection against a wide variety of bacteria, there are currently no analogous clinically available broad-spectrum antiviral agents. An international research team has more

FMI researchers have identified a synthetic protein that dampens the activity of a cellular pathway involved in viral infection. The findings could help to develop drugs that combat viruses such as influenza A and Zika. Influenza A virus affects millions of people worldwide and can have serious comp more

Less than three years after its foundation, the start-up G.ST Antivirals reaches a major milestone in the development of its lead asset and begins clinical phase I at the Vienna General Hospital. G.ST Antivirals is testing a nasal spray, which was developed specifically for use against colds and oth more

Viruses, Vol. 10, Pages 337: Visualizing Viral Infection In Vivo by Multi-Photon Intravital Microscopy Viruses doi: 10.3390/v10060337 Authors: Xaver Sewald Viral pathogens have adapted to the host organism to exploit the cellular machinery for virus replication and to modulate the hos more

Viruses, Vol. 10, Pages 314: Understanding Oxidative Stress in Aedes during Chikungunya and Dengue Virus Infections Using Integromics Analysis Viruses doi: 10.3390/v10060314 Authors: Jatin Shrinet Neel Sarovar Bhavesh Sujatha Sunil Arboviral infection causes dysregulation of casca more

Viruses, Vol. 10, Pages 302: Preclinical Testing of an Oncolytic Parvovirus in Ewing Sarcoma: Protoparvovirus H-1 Induces Apoptosis and Lytic Infection In Vitro but Fails to Improve Survival In Vivo Viruses doi: 10.3390/v10060302 Authors: Jeannine Lacroix Zoltán Kis Rafael Josupeit Fr more