T Cells

News T Cells

• Cancer treatment: A researcher makes breakthrough immunotherapy discovery

  Dr Christopher E. Rudd, a researcher at the Centre de recherche de l'Hôpital Maisonneuve-Rosemont (CR-HMR) and Université de Montréal, has discovered a new cell therapy approach that boosts the immune response of T lymphocytes to malignant tumours. "Our work has identified a new T-cell protein that more

• Merck Becomes the First to Use Acoustic Technology for Cell Therapy Manufacturing

  Merck announced it has acquired FloDesign Sonics, of Wilbraham, Massachusetts, USA, developer of a unique acoustic cell processing platform for the industrialization of cell and gene therapy manufacturing. Financial details were not disclosed. “Chimeric antigen receptor T cell therapies, or CAR-T fo more

• Successful T cell engineering with gene scissors
  

  The idea of genetically modifying a patient’s own immune cells and deploying them against infections and tumors has been around since the 1980s. But to this day modified T cells are still not as effective as natural T cells and have been only been of limited clinical value. Using the new CRISPR-Cas9 more

Videos T Cells

Killer T Cell: The Cancer Assassin

How does a Killer T Cell Kill its target?The new film captures the behaviour of cytotoxic T cells – the body’s ‘serial killers’ – as they hunt down and eliminate cancer cells before moving on to their next target. more

‘Cellbots’ Chase Down Cancer

Engineered human immune cells can precisely locate diseased cells anywhere in the body and execute a wide range of customizable responses, including the delivery of drugs or other therapeutic payloads directly to tumors or other unhealthy tissues. more

White papers T Cells

• Dynamics of Kinases Involved in Cell Growth Using the xCELLigence System
  

  Studies investigating endogenous cellular regulatory mechanisms have substantially pushed the application of high-throughput screens. RNA interference has developed into an extremely powerful tool for mediating the loss-of-function of specific mRNA m more

Publications T Cells

• Prevention and treatment of relapse after stem cell transplantation by cellular therapies

  Despite recent advances in reducing therapy-related mortality after allogeneic stem cell transplantation (alloSCT) relapse remains the major cause of treatment failure and little progress has been achieved in the last decades. At the 3rd International Workshop on Biology, Prevention, and Treatment o more

• Viruses, Vol. 10, Pages 273: Following Acute Encephalitis, Semliki Forest Virus is Undetectable in the Brain by Infectivity Assays but Functional Virus RNA Capable of Generatin ...

  Viruses, Vol. 10, Pages 273: Following Acute Encephalitis, Semliki Forest Virus is Undetectable in the Brain by Infectivity Assays but Functional Virus RNA Capable of Generating Infectious Virus Persists for Life Viruses doi: 10.3390/v10050273 Authors: Rennos Fragkoudis Catherine M. Dixon more

• Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig

  by Katie Tungatt, Garry Dolton, Sophie B. Morgan, Meriem Attaf, Anna Fuller, Thomas Whalley, Johanneke D. Hemmink, Emily Porter, Barbara Szomolay, Maria Montoya, John A. Hammond, John J. Miles, David K. Cole, Alain Townsend, Mick Bailey, Pierre J. Rizkallah, Bryan Charleston, Elma Tchilian, Andrew more