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News Superbugs

  • Bid to beat superbugs boosted by immune defence discovery

    The fight against superbugs could be helped by the discovery of a potential therapy based on the body's natural immune defences. Scientists have found that a molecule produced by the body - called LL-37 - changes the way cells behave when they are invaded by bacteria. The molecule acts like a fire a more

  • New compound which kills antibiotic-resistant superbugs discovered

    A new compound which visualises and kills antibiotic resistant superbugs has been discovered by scientists at the University of Sheffield and Rutherford Appleton Laboratory (RAL). The team, led by Professor Jim Thomas, from the University of Sheffield's Department of Chemistry, is testing new compou more

  • University spinout receives £1.2 million to tackle antimicrobial resistance

    Amprologix Limited, a University of Plymouth spinout company, has won a £1.2 million contract from the Department for Health and Social Care to accelerate development and scale up its lead antibiotic candidate to tackle antimicrobial resistant MRSA and related superbugs. Amprologix was established i more

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Publications Superbugs

  • Macromol. Biosci. 9/2017

    Back Cover: Acne caused by Propionibacterium acnes is treated with antibiotics but effectiveness is often compromised by resistance and development of “superbugs”. An alternative antimicrobial polycation without resistance buildup is described. The results point to a promising pathway for polycat more

  • [Review] Mechanisms of bacterial persistence during stress and antibiotic exposure

    ### BACKGROUND The escalating crisis of multidrug resistance is raising fears of untreatable infections caused by bacterial “superbugs.” However, many patients already suffer from infections that are effectively untreatable due to innate bacterial mechanisms for persistence. This phenomenon is caus more

  • A Hydrogel‐Based Localized Release of Colistin for Antimicrobial Treatment of Burn Wound Infection

    There is an urgent unmet medical need for new treatments for wound and burn infections caused by multidrug‐resistant Gram‐negative “superbugs,” especially the problematic Pseudomonas aeruginosa. In this work, the incorporation of colistin, a potent lipopeptide into a self‐healable hydrogel (via dy more

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