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Prions

News Prions

  • Provocative prions may protect yeast cells from stress

    Prions have a notorious reputation. They cause neurodegenerative disease, namely mad cow/Creutzfeld-Jakob disease. And the way these protein particles propagate – getting other proteins to join the pile – can seem insidious. Yet prion formation could represent a protective response to stress, resear more

  • Impact of prion proteins on the nerves revealed for the first time

    When prion proteins mutate, they trigger mad cow and Creutzfeldt-Jakob disease. Although they are found in virtually every organism, the function of these proteins remained unclear. Researchers from the University of Zurich and the University Hospital Zurich now demonstrate that prion proteins, coup more

  • Iowa State researchers describe copper-induced misfolding of prion proteins

    Iowa State University researchers have described with single-molecule precision how copper ions cause prion proteins to misfold and seed the misfolding and clumping of nearby prion proteins. The researchers also found the copper-induced misfolding and clumping is associated with inflammation and dam more

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Definition

Prion

Prion A prion ( In general usage, prion can refer to both the theoretical unit of infection or the specific protein (e.g., PrP) that is thought to be the infective agent, whether or not it is in an infective state. Prion diseases can result ... more

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