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Pluripotency

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  • Tracking protein’s role in stem cell function

    MCL-1 is a member of the BCL-2 family of proteins important for blocking apoptosis, or programmed cell death. Many types of cancer cells escape the body’s effort to kill them by overexpressing MCL-1. However, new evidence from Vanderbilt University researchers indicates that MCL-1 also helps maintai more

  • First stem cells using CRISPR genome activation created

    In a scientific first, researchers at the Gladstone Institutes turned skin cells from mice into stem cells by activating a specific gene in the cells using CRISPR technology. The innovative approach offers a potentially simpler technique to produce the valuable cell type and provides important insig more

  • Genetic cross-talk key to cell balance

    Competing regulatory genes "talk" to each other to maintain balance of cell state, according to new research from the Stowers Institute for Medical Research. In a study Stowers scientists Bony De Kumar, Ph.D., and Robb Krumlauf, Ph.D., provide evidence of direct cross-regulatory feedback, or cross-t more

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