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Boosting the immune system could offer a radical new way to treat Alzheimer’s disease, according to Dr Michal Schwartz from the Weizmann Institute of Science in Israel. Experiments in mice have shown that targeting immune cells arrested the damage to the brain and helped preserve cognition. For man more
A pre-clinical study led by Indiana University scientists reports a promising step forward in the search for pain relief methods without the addictive side effects behind the country's current opioid addiction crisis. The research finds that the use of compounds called positive allosteric modulators more
Saint Louis University researcher Daniela Salvemini, Ph.D., reports discovering a key molecular pathway that drives cancer-related bone pain while providing a potential solution with a drug that already is on the market. Salvemini, who is a professor of pharmacology and physiology at SLU, studies ma more
This one goes out to all of our slasher flick fans out there. We love horror films here at Reactions, so in honor of all of those chased by monsters, villains, and zombies out there, we decided to take a closer look at what happens chemically in your brain and body right before you die. more
There are some things you wouldn't wish upon even your worst enemy. Stepping on Legos being no such exception. The mind bending pain of a bare foot pressing down on a Lego is one of the worst known to humanity, but how does something so innocent looking create such an intense feeling? We're talk ... more
This one looks at the Schmidt Pain Index, developed by entomologist Dr. Justin Schmidt to rank the pain of the various insect stings and bites he experienced as part of his work. more
The idea for this graphic came to me whilst saving the chilli peppers from a forlorn looking, aphid-infested chilli plant that’s probably on its metaphorical last legs. I thought it would be quite interesting to look at the origin of the heat in chilli peppers, and how this can be quantified. A fami more
The idea for this graphic came to me whilst saving the chilli peppers from a forlorn looking, aphid-infested chilli plant that’s probably on its metaphorical last legs. I thought it would be quite interesting to look at the origin of the heat in chilli peppers, and how this can be quantified. A fami more
by Eleonora Borelli, Davide Crepaldi, Carlo Adolfo Porro, Cristina Cacciari Despite the flourishing research on the relationships between affect and language, the characteristics of pain-related words, a specific type of negative words, have never been systematically investigated from a psycholin more
by Ben R. Hofma, Hannah R. Wardill, Chris Mavrangelos, Melissa A. Campaniello, David Dimasi, Joanne M. Bowen, Scott D. Smid, Claudine S. Bonder, Elizabeth A. Beckett, Patrick A. Hughes Background Inflammatory Bowel Disease (IBD) is characterized by overt inflammation of the intestine and is typic more
Pain The pain relief afforded by morphine and other opioids comes with the cost of behavioral side effects and high addiction potential. He et al. found that the analgesic response to morphine could be enhanced by compounds that activate the peripheral sensory neuron–localized receptor MrgC11 in more
Mad pain and Martian pain Brief overview Mad Pain and Martian Pain is a philosophical article written by David Kellogg Lewis . Lewis argues that a theory of pain must be able to reflect the most basic intuitions of both functionalism and ident ... more
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