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Pain is mediated through specialized nerve cells that are activated when potentially harmful things affect various parts of our bodies. These nerve cells have a special ion channel that has a key role in starting the electrical impulse that signals pain and is sent to the brain. According to a new s more
Abnormal levels of stress hormones such as adrenaline and cortisol are linked to a variety of mental health disorders, including depression and posttraumatic stress disorder (PTSD). MIT researchers have now devised a way to remotely control the release of these hormones from the adrenal gland, using more
Together with colleagues from Shanghai, Brussels, Canada and the USA, researchers from the University of Bonn have uncovered the binding mechanism of an important pain receptor. The results facilitate the development of new active substances. The opioids used today to treat severe pain can be addict more
This one goes out to all of our slasher flick fans out there. We love horror films here at Reactions, so in honor of all of those chased by monsters, villains, and zombies out there, we decided to take a closer look at what happens chemically in your brain and body right before you die. more
There are some things you wouldn't wish upon even your worst enemy. Stepping on Legos being no such exception. The mind bending pain of a bare foot pressing down on a Lego is one of the worst known to humanity, but how does something so innocent looking create such an intense feeling? We're talk ... more
This one looks at the Schmidt Pain Index, developed by entomologist Dr. Justin Schmidt to rank the pain of the various insect stings and bites he experienced as part of his work. more
The idea for this graphic came to me whilst saving the chilli peppers from a forlorn looking, aphid-infested chilli plant that’s probably on its metaphorical last legs. I thought it would be quite interesting to look at the origin of the heat in chilli peppers, and how this can be quantified. A fami more
The idea for this graphic came to me whilst saving the chilli peppers from a forlorn looking, aphid-infested chilli plant that’s probably on its metaphorical last legs. I thought it would be quite interesting to look at the origin of the heat in chilli peppers, and how this can be quantified. A fami more
by Eleonora Borelli, Davide Crepaldi, Carlo Adolfo Porro, Cristina Cacciari Despite the flourishing research on the relationships between affect and language, the characteristics of pain-related words, a specific type of negative words, have never been systematically investigated from a psycholin more
by Ben R. Hofma, Hannah R. Wardill, Chris Mavrangelos, Melissa A. Campaniello, David Dimasi, Joanne M. Bowen, Scott D. Smid, Claudine S. Bonder, Elizabeth A. Beckett, Patrick A. Hughes Background Inflammatory Bowel Disease (IBD) is characterized by overt inflammation of the intestine and is typic more
Pain The pain relief afforded by morphine and other opioids comes with the cost of behavioral side effects and high addiction potential. He et al. found that the analgesic response to morphine could be enhanced by compounds that activate the peripheral sensory neuron–localized receptor MrgC11 in more
Mad pain and Martian pain Brief overview Mad Pain and Martian Pain is a philosophical article written by David Kellogg Lewis . Lewis argues that a theory of pain must be able to reflect the most basic intuitions of both functionalism and ident ... more
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