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Obesity − as research in the past decade has shown − is first and foremost a brain disease. Researchers at Helmholtz Zentrum München, partners in the German Center for Diabetes Research, have now discovered a molecular switch that controls the function of satiety neurons and therefore body weight. T more
Have you ever wondered why we crave the very foods that we try to avoid when dieting? Or wish there was a way to turn off the craving? Researchers from The University of Texas Medical Branch at Galveston have identified new brain circuits that may act as a brake on binge eating and junk food craving more
January 2019 saw the launch of the EU research project EDCMET, in which scientists from the German Federal Institute for Risk Assessment (BfR) are also involved. EDCMET stands for "Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome path-ways" and is aimed more
Dysregulation of cellular energy metabolism is a common factor in a variety of disorders including diabetes and obesity as well as cancer more
Raspberries, like all fruits, contain a complex mix of organic compounds. Unlike many fruits, however, raspberries have the less common distinction of lending their name to the compound that is a major contributor to their aroma – and one of the compounds that contributes to their flavour has also b more
Baicalin is a major flavonoid component from the herbal medicine Scutellaria baicalensis that has been shown to have an antisteatosis effect. Through quantitative chemoproteomic profiling, we discovered that baicalin acts as a natural allosteric activator of carnitine palmitoyltransferase 1 (CPT1), more
Marine Drugs, Vol. 16, Pages 216: Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota Marine Drugs doi: 10.3390/md16060216 Authors: Erin K. Crowley Caitriona M. Long-Smith Amy Murphy Elaine Patterson Kiera Murphy more
Obesity has become a major epidemic around the globe, with fatal comorbidities such as type 2 diabetes, heart disease, and cancer that have led to alarming health concerns in modern medicine. Although excess adipose tissue is associated with negative metabolic outcomes, the physiological functions o more
BMI View: Based on new historical data for Peru's pharmaceutical sales in 2010 and 2011, we have reevaluated our forecasts for the country. The total market, worth PEN3.90bn (US$1.42bnm) in 2011, is now expected to post a slightly higher five-year compound annual growth rate (CAGR) of 7.6%, as measu more
BMI View: A key theme in the South Korean pharmaceutical market is the government's incessant pharmaceutical price cuts that have created a cloud of uncertainty over the sector. In addition, a price cut announced in August 2011 is set to be effective later in 2012, which will mean an average 17% pri more
BMI View: Aligning with our view that we expect the French government to engage in more concerted fiscal consolidation to mount over the coming quarters, particularly following the elections held in early 2012, we believe that the publication of Mutualité Française's data on the falling volume sales more
Central obesity Central obesity (or "apple-shaped" or "masculine" obesity ) occurs when the main deposits of body fat are localised around the abdomen and the upper body. Central obesity is correlated with visceral fat . Associations ... more
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