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58 Current news about the topic muscular dystrophy

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A genetic chaperone for healthy aging?

14-Aug-2019

Researchers at the Max Delbrück Center for Molecular Medicine (MDC) have identified an epigenetic mechanism that appears to strongly influence healthy aging. It’s a protein that controls muscle integrity, lifespan and levels of an essential sugar. How does one protein have that much ...

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A golden ticket to faster muscle recovery

Gold nanoparticles with cytokines reduce inflammation and promote muscle fiber regeneration

04-Oct-2018

Anyone who has ever torn or injured a muscle knows that swelling, redness, and pain soon follow the injury: classic signs of inflammation. Inflammation is the body’s natural response to promote healing, but prolonged, excess inflammation in the muscles can contribute to the progression of chronic ...

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New technique could bring earlier diagnoses for muscular dystrophy, ALS and similar disorders

07-May-2018

A new blood test could reveal the genetic roots of muscular dystrophy, amyotrophic lateral sclerosis and other disorders caused by the expansion of DNA repeats, potentially helping doctors diagnose their patients’ conditions sooner. The findings by University of Florida Health researchers and ...

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Gene therapy prevents, reverses multiple sclerosis in animal model

26-Sep-2017

Multiple sclerosis can be inhibited or reversed using a novel gene therapy technique that stops the disease's immune response in mouse models, University of Florida Health researchers have found. By combining a brain-protein gene and an existing medication, the researchers were able to prevent ...

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Designed Proteins to Treat Muscular Dystrophy

30-Jun-2017

The cell scaffolding holds muscle fibers together and protects them from damage. Individuals who suffer from muscular dystrophy often lack essential components in this cell scaffold. As a result, their muscles lack strength and become progressively weaker. The research team of Prof. Markus Rüegg ...

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How are long strands of DNA packed into tiny cells?

29-Jun-2017

Scientists are a step closer to understanding how DNA, the molecules that carry all of our genetic information, is squeezed into every cell in the body. How DNA is "packaged" in cells influences the activity of our genes and our risk for disease. Elucidating this process will help researchers in ...

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Drug pair slows progression of muscular dystrophy in animal models

19-Apr-2017

A pair of protein-inhibiting compounds is effective at slowing the progression of a form of muscular dystrophy in animal models, a group of University of Florida Health researchers has found. The compounds of this novel drug class are particularly intriguing for use by Duchenne muscular dystrophy ...

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New study shows circular RNA can encode for proteins

27-Mar-2017

A group of scientists in Israel and Germany, led by Prof. Sebastian Kadener from the Hebrew University of Jerusalem, have discovered a protein-encoding function for circular RNA. This kind of RNA molecule is highly active in brain cells and could play an important role in neurodegenerative ...

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Molecular structure of the cell nucleoskeleton revealed for the first time

03-Mar-2017

Using 3D electron microscopy, structural biologists from the University of Zurich succeeded in elucidating the architecture of the lamina of the cell nucleus at molecular resolution for the first time. This scaffold stabilizes the cell nucleus in higher eukaryotes and is involved in organizing, ...

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New judicial decisions at odds with EMA’s efforts to allow access to documents on medicines

EMA appeals interim measures

04-Oct-2016

The European Medicines Agency (EMA) has appealed two interim orders by the President of the General Court of the European Union (EU) to suspend the release of documents requested by third parties under Regulation (EC) no. 1049/2001, the so-called “Transparency Regulation”. The first order blocked ...

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