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28 Current news about the topic glucose metabolism

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New target emerging for treating diabetes-related blood vessel damage

23-Oct-2017

A key enzyme that helps our proteins fold and function properly may also be a good therapeutic target to improve blood vessel health in diseases like diabetes and atherosclerosis, scientists say. The enzyme is protein disulfide isomerase, or PDI, and scientists have increasing evidence that PDI ...

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Multiple roles of glucose metabolism in platelet activation and survival identified

07-Aug-2017

Platelets, the cells in blood that enable clotting, are highly reliant on their ability to metabolize glucose, according to a new study by researchers at the University of Iowa. The findings may have implications for understanding the increased risk of thrombosis--blood clots inside blood ...

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Computer simulation of protein synthesis reveals high complexity of cell machinery

20-Mar-2017

Life depends on proteins. These molecules are produced continually in our cells, which act as microscopic production lines - but the process is so complex we have barely begun to understand it. Exploring protein synthesis may, however, be the key to revealing how the body controls the thousands ...

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A new regulator in glucose metabolism

11-Nov-2016

Diabetes mellitus is a chronic disease that has become increasingly prevalent in the population: More than six million people are affected by the disease alone in Germany. It is characterized by a disruption of the glucose metabolism and (except for type 1 diabetes) an impaired response of the ...

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Using magnetic forces to control neurons, study finds brain is vital in glucose metabolism

31-Mar-2016

To learn what different cells do, scientists switch them on and off and observe what the effects are. There are many methods that do this, but they all have problems: too invasive, or too slow, or not precise enough. Now, a new method to control the activity of neurons in mice, devised by ...

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Fish Oil-Diet Benefits May be Mediated by Gut Microbes

01-Sep-2015

Diets rich in fish oil versus diets rich in lard produce very different bacteria in the guts of mice, reports a study from Sahlgrenska Academy. The researchers transferred these microbes into other mice to see how they affected health. The results suggest that gut bacteria share some of the ...

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Infections damage our ability to form spatial memories

28-Jan-2014

Increased inflammation following an infection impairs the brain's ability to form spatial memories – according to new research. The impairment results from a decrease in glucose metabolism in the brain's memory centre, disrupting the neural circuits involved in learning and memory. Inflammation ...

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New player in obesity

09-Jan-2014

A new neuroscience study sheds light on the biological underpinnings of obesity. The in vivo study, published in the January 8 issue of the Journal of Neuroscience, reveals how a protein in the brain helps regulate food intake and body weight. The findings reveal a potential new avenue for the ...

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A rescuer for vital tumor-suppressor

Enzyme intervenes when cancer-fighting PTEN is bound for cell's protein-destroying machinery

29-Nov-2013

A protector for PTEN, a tumor-thwarting protein often missing in cancer cells, has emerged from research led by scientists at The University of Texas MD Anderson Cancer Center published online at Nature Cell Biology. "We discovered that the enzyme USP13 stabilizes the PTEN protein by reversing a ...

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Brain may play key role in blood sugar metabolism and development of diabetes

Normal blood sugar regulation is a partnership between the pancreas and the brain

08-Nov-2013

A growing body of evidence suggests that the brain plays a key role in glucose regulation and the development of type 2 diabetes. If the hypothesis is correct, it may open the door to entirely new ways to prevent and treat this disease, which is projected to affect one in three adults in the ...

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