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46 Current news about the topic chronic lymphocytic leukemiarss
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Chemical signature of chronic lymphocytic leukemia already present in the precancerous stage
B-cell lymphocytosis, a condition in which individuals have increased levels of particular white blood cells, in some cases leads to blood cancer. As an international team of researchers now shows in samples from patients, both diseases exhibit similar epigenetic signatures that are forming very ...
Mice with leukemia were cured
MDC researchers have developed a new approach to CAR T-cell therapy. The team has shown in Nature Communications that the procedure is very effective, especially when it comes to fighting follicular lymphomas and chronic lymphocytic leukemia, the most common type of blood cancer in adults. The ...
Compounds that inhibit metabolic enzyme IL4I1 could open up new opportunities for cancer therapy
The metabolic enzyme IL4I1 (interleukin-4-induced-1) promotes the spread of tumor cells and suppresses the immune system. This was discovered by scientists from the Berlin Institute of Health (BIH) together with colleagues from the German Cancer Research Center (DKFZ) in Heidelberg. The enzyme is ...
Fueled by a multimillion dollar grant from the state's stem cell agency, researchers at University of California San Diego School of Medicine, in collaboration with local biotechnology company Oncternal Therapeutics, have launched a phase Ib/II clinical trial to evaluate the combined ...
Not all melanomas are created equal. While most melanomas appear on the skin as the result of sun exposure, a small subset of melanomas arise spontaneously from mucosal tissues. And while targeted treatments and immunotherapies have dramatically improved the prognosis for many patients with ...
Older adults with chronic lymphocytic leukemia may now have an alternative to toxic chemotherapy as their first treatment, according to a national study by a UR Medicine Wilmot Cancer Institute oncologist and reported in the New England Journal of Medicine. The phase 3 clinical trial compared a ...
AbbVie announced that a Phase 2 trial of its investigational medicine venetoclax met its primary endpoint of achievingoverall response rates in patients with relapsed/refractory or previously untreated chronic lymphocytic leukemia (CLL) with 17p deletion, according to an independent review ...
Imbruvica and Zydelig to be used in different forms of blood cancers
The European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP), at its July meeting, recommended granting marketing authorisations for two new medicines with novel mechanisms of action for the treatment of different forms of rare cancers of the blood. Imbruvica ...
Medicine represents new treatment option for patients with rare life-threatening disease
The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended marketing authorisation for Gazyvaro (obinutuzumab) in combination with the cancer medicine chlorambucil for the treatment of adults with previously untreated chronic lymphocytic ...
Study demonstrates technique to create better anti-cancer agents, arthritis drugs, and more
Many drugs such as agents for cancer or autoimmune diseases have nasty side effects because while they kill disease-causing cells, they also affect healthy cells. Now a new study has demonstrated a technique for developing more targeted drugs, by using molecular "robots" to hone in on more ...