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80 Current news about the topic chemical biology

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New chemical tools to modify and study biomolecules

08-Jul-2019

Understanding the structure and metabolism of cells and living organisms is essential for the development of new drugs and diagnostics. The availability of chemical tools that allow scientists to edit biomolecules, like proteins, with atom-level resolution have greatly contributed to the progress ...

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Advancing stem cell therapy with biodegradable scaffold

New technology is aimed at central nervous system diseases and injuries

06-Nov-2018

Rutgers scientists have created a tiny, biodegradable scaffold to transplant stem cells and deliver drugs, which may help treat Alzheimer's and Parkinson's diseases, aging brain degeneration, spinal cord injuries and traumatic brain injuries. Stem cell transplantation, which shows promise as a ...

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New method measures single molecules from nanoliter of blood in real time

09-Oct-2018

University of Groningen scientists, led by Associate Professor of Chemical Biology Giovanni Maglia, have designed a nanopore system that is capable of measuring different metabolites simultaneously in a variety of biological fluids, all in a matter of seconds. The electrical output signal is ...

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Cellular clean-up can also sweep away forms of cancer

13-Nov-2017

Two new research papers reinforce the benefits of a novel therapy that hijacks the cell’s own protein degradation machinery to destroy cancer cells, Yale researchers report Nov. 9 in the journal Cell Chemical Biology. The new approach to drug discovery, called Proteolysis Targeting Chimeras or ...

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Revolutionary process could signal new era for gene synthesis

13-Sep-2017

A team of scientists led by the University of Southampton has demonstrated a groundbreaking new method of gene synthesis - a vital research tool with real-world applications in everything from growing transplantable organs to developing treatments for cancer. Current methods for synthesizing ...

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The science of fluoride flipping

25-Aug-2017

So much of what happens inside cells to preserve health or cause disease is so small or time-sensitive that researchers are just now getting glimpses of the complexities unfolding in us every minute of the day. UNC School of Medicine researchers have discovered one such complexity -- a previously ...

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Drug design strategy boosts the odds against resistance development

16-Jun-2017

A new rational drug design technique that uses a powerful computer algorithm to identify molecules that target different receptor sites on key cellular proteins could provide a new weapon in the battle against antibiotic resistance, potentially tipping the odds against the bugs. The technique, ...

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Structure of tuberculosis drug target determined

10-Apr-2017

Rutgers University scientists have determined the three-dimensional structure of the target of the first-line anti-tuberculosis drug rifampin. They have also discovered a new class of potential anti-tuberculosis drugs that kill rifampin-resistant and multi-drug-resistant tuberculosis ...

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Future of regenerative medicine looks bright with new funding boost

04-Apr-2017

The UK Regenerative Medicine Platform (UKRMP), is to receive a further multimillion funding commitment to help realise the goal of accelerating scientific discoveries in regenerative therapies to clinical application. The Platform is a joint initiative between the Medical Research Council (MRC), ...

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New technology offers fast peptide synthesis

02-Mar-2017

Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections. To help speed up the manufacturing process, MIT researchers have designed a machine that can rapidly ...

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