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08-Aug-2019 - Modern light microscopic techniques provide extremely detailed insights into organs, but the terabytes of data they produce are usually nearly impossible to process. New software, developed by a team led by MDC scientist Dr. Stephan Preibisch and now presented in Nature Methods, is helping ...
12-Jul-2019 - A German-Swiss team around Professor Oliver Daumke from the MDC has investigated how a protein of the dynamin family deforms the inner mitochondrial membrane. Mitochondria are the powerhouses of our cells, generating energy in the form of chemical compounds such as ATP. To do this job ...
06-Mar-2019 - Lil BUB has drawn millions of followers across the internet for her cute appearance. Behind the celebrity cat’s unique features is a combination of two rare genetic variants, three molecular biologists from Germany and the US report. The results of their crowdfunded project “LilBUBome” are now ...
17-Dec-2018 - he fatty acid propionate helps defend against the effects of high blood pressure, including atherosclerosis and heart tissue remodeling, a study on mice has found. Gut bacteria produce the substance – which calms the immune cells that drive up blood pressure – from natural dietary fiber. “You are ...
10-Sep-2018 - The seizures typically begin in the first months of life. It often takes years, however, before those suffering from the rare glucose transporter type 1 (Glut1) deficiency syndrome obtain a correct diagnosis. If the disorder goes untreated, affected children experience developmental delay and ...
14-Sep-2017 - In the largest transcriptome study to date, an international research team analysed the RNA of transplanted hearts and discovered a number of new risk factors for dilated cardiomyopathy and other heart conditions which could thus be recognised more easily in future. We know of many genes with ...
04-Sep-2017 - In a technological tour de force, Berlin scientists have created a virtual model of an early fly embryo. Its interactive interface allows researchers to explore the blueprint that underlies development at unprecedented spatial resolution and predict which cells express which genes. After 13 rapid ...
16-Aug-2017 - For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders. While hundreds ...
28-Apr-2017 - Immunotherapy with T-cells offers great hope to people suffering from cancer. Some initial successes have already been made in treating blood cancer, but treating solid tumors remains a major challenge. The signaling molecule interferon gamma, which is produced by T-cells, plays a key role in the ...
19-Apr-2017 - Many tumors are thought to depend on glutamine, suggesting glutamine deprivation as therapeutic approach, but a new study shows that this effect might have been overestimated. Most cancers require large amounts of glutamine for rapid growth and there are numerous studies indicating that they ...
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