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Metformin

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  • Combinig diabetes drug and immunotherapy against breast cancer

    MYC, a gene with high cancer-initiating potential, is overexpressed in over 40% of breast cancers. While MYC programs breast cancer cells to build more macromolecules (anabolic metabolism) it also creates a metabolic vulnerability by making them more sensitive to a type of cell death known as apopto more

  • Lethal combination: Drug cocktail turns off the juice to cancer cells

    A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug c more

  • How obesity drives colon cancer in mice

    Obesity, which is on the rise worldwide, has been linked to colon cancer but the mechanism has been a mystery. In a new study, Yale researchers and their co-authors have uncovered how obesity drives tumor growth in mice, revealing potential strategies to combat the disease. Led by assistant professo more

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Metformin

Metformin Metformin (INN ; trade names Glucophage, Riomet, Fortamet, Glumetza, Diabex, Diaformin, and others) () is an oral anti-diabetic drug from the biguanide class. It is the first-line drug of choice for the treatment of type 2 diabetes ... more

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