Ion Channels

News Ion Channels

• Why are neuron axons long and spindly?
  

  A team of bioengineers at UC San Diego has answered a question that has long puzzled neuroscientists, and may hold a key to better understanding the complexities of neurological disorders: Why are axons, the spindly arms extending from neurons that transmit information from neuron to neuron in the b more

• Prof. Dr. Peter Hegemann receives Otto Warburg Medal 2018
  

  On March 23rd, Prof. Dr. Peter Hegemann from the Humboldt-Universität zu Berlin has been awarded the Otto Warburg Medal 2018. The Society for Biochemistry and Molecular Biology (GBM e.V.) as well as its cooperation partners, the information analytics company Elsevier and Biochimica et Biophysica Act more

• Scorpion venom component can reduce severity of rheumatoid arthritis
  

  A treatment that improves the lives of nearly 1.3 million people with rheumatoid arthritis might one day originate from scorpion venom. A group of researchers led by Dr. Christine Beeton at Baylor College of Medicine has found that one of the hundreds of components in scorpion venom can reduce the s more

Videos Ion Channels

New Structure of a Calcium-Shuttling Molecule Could Help Scientists Target Aggressive Cancers

Scientists have captured new images of a calcium-shuttling molecule that has been linked to aggressive cancers. The three-dimensional structure could help researchers develop novel therapies and diagnostic tools for diseases that are caused by a malfunction in calcium adsorption. more

White papers Ion Channels

• New Standard in Electrophysiology and Deep Tissue Imaging
  

  The function of nerve and muscle cells relies on ionic currents flowing through ion channels. These ion channels play a major role in cell physiology. One way to investigate ion channels is to use patch clamping. This method allows investigation of i more

• Predictor(TM) hERG Fluorescence Polarization Assay Kit performed on the PHERAstar/PHERAstar Plus
  

  The potential for cardiotoxic side-effects continues to challenge the development of small molecule based therapies. These intolerable side-effects are often precipitated by drug-induced long QT syndrome (LQT), which is often linked to blocking the h more

• RealTime ready - Function Tested qPCR Assays Based on the Universal ProbeLibrary Technology
  

  RealTime ready qPCR Assays redefine real-time qPCR because each assay is function-tested in PCR and qualified under strict criteria to assure superior performance. The RealTime ready Assays are based on the well-known Universal ProbeLibrary (UPL) tec more

Publications Ion Channels

• Stochastic shielding and edge importance for Markov chains with timescale separation

  by Deena R. Schmidt, Roberto F. Galán, Peter J. Thomas Nerve cells produce electrical impulses (“spikes”) through the coordinated opening and closing of ion channels. Markov processes with voltage-dependent transition rates capture the stochasticity of spike generation at the cost of complex, tim more

• A biophysical mechanism for preferred direction enhancement in fly motion vision

  by Alexander Borst Seeing the direction of motion is essential for survival of all sighted animals. Consequently, nerve cells that respond to visual stimuli moving in one but not in the opposite direction, so-called ‘direction-selective’ neurons, are found abundantly. In general, direction select more

• Marine Drugs, Vol. 16, Pages 208: Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails

  Marine Drugs, Vol. 16, Pages 208: Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails Marine Drugs doi: 10.3390/md16060208 Authors: Nikita Abraham Richard J. Lewis Marine cone snails are a large family of gastropods that have evolved highly potent venoms for predat more