Ion Channels

News Ion Channels

• Ion channel VRAC enhances immune response against viruses
  

  VRAC/LRRC8 chloride channels do not only play a decisive role in the transport of cytostatics, amino acids and neurotransmitters. They can also transport the important messenger substance cGAMP from cell to cell and thus strengthen the immune response to infections with DNA viruses. This has now bee more

• Scientists develop DNA microcapsules with built-in ion channels
  

  A Research group led by Tokyo Tech reports a way of constructing DNA-based microcapsules that hold great promise for the development of new functional materials and devices. They showed that tiny pores on the surface of these capsules can act as ion channels. Their study will accelerate advances in more

• Why are neuron axons long and spindly?
  

  A team of bioengineers at UC San Diego has answered a question that has long puzzled neuroscientists, and may hold a key to better understanding the complexities of neurological disorders: Why are axons, the spindly arms extending from neurons that transmit information from neuron to neuron in the b more

Videos Ion Channels

New Structure of a Calcium-Shuttling Molecule Could Help Scientists Target Aggressive Cancers

Scientists have captured new images of a calcium-shuttling molecule that has been linked to aggressive cancers. The three-dimensional structure could help researchers develop novel therapies and diagnostic tools for diseases that are caused by a malfunction in calcium adsorption. more

White papers Ion Channels

• RealTime ready - Function Tested qPCR Assays Based on the Universal ProbeLibrary Technology
  

  RealTime ready qPCR Assays redefine real-time qPCR because each assay is function-tested in PCR and qualified under strict criteria to assure superior performance. The RealTime ready Assays are based on the well-known Universal ProbeLibrary (UPL) tec more

Publications Ion Channels

• Stochastic shielding and edge importance for Markov chains with timescale separation

  by Deena R. Schmidt, Roberto F. Galán, Peter J. Thomas Nerve cells produce electrical impulses (“spikes”) through the coordinated opening and closing of ion channels. Markov processes with voltage-dependent transition rates capture the stochasticity of spike generation at the cost of complex, tim more

• A biophysical mechanism for preferred direction enhancement in fly motion vision

  by Alexander Borst Seeing the direction of motion is essential for survival of all sighted animals. Consequently, nerve cells that respond to visual stimuli moving in one but not in the opposite direction, so-called ‘direction-selective’ neurons, are found abundantly. In general, direction select more

• Marine Drugs, Vol. 16, Pages 208: Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails

  Marine Drugs, Vol. 16, Pages 208: Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails Marine Drugs doi: 10.3390/md16060208 Authors: Nikita Abraham Richard J. Lewis Marine cone snails are a large family of gastropods that have evolved highly potent venoms for predat more