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Inflammation

News Inflammation

  • From gut to space

    Scientists from Umeå university have shown how the yeast Candida albicans can modulate and adapt to low oxygen levels in different body niches to cause infection and to harm the host. Studying adaption to hypoxic or anoxic niches is particularly fruitful, since it helps us to understand the pathogen more

  • Faulty immune receptor could be reason why many face HIV complications

    For HIV patients, treatments that control the infection have come a long way. But many still struggle with a host of other disease-related complications such as neurocognitive disorders, cardiovascular issues, diabetes and chronic inflammation. Why these complications occur isn't exactly known, but more

  • A golden ticket to faster muscle recovery

    Anyone who has ever torn or injured a muscle knows that swelling, redness, and pain soon follow the injury: classic signs of inflammation. Inflammation is the body’s natural response to promote healing, but prolonged, excess inflammation in the muscles can contribute to the progression of chronic di more

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The Chemistry of Stinging Nettles

Doubtless the majority of people reading this will, at some point in their life, have had the unpleasant experience of being stung by stinging nettles. But what chemicals do stinging nettles contain that elicit this effect? Further to that, a commonly espoused remedy for the stings, in the UK at lea more

Publications Inflammation

  • Inflammatory decoy control

    Sepsis Bacterial infection can lead to sepsis, inflammation, and death. Li et al. found that the long noncoding RNA MEG3-4 and the mRNA encoding the proinflammatory cytokine interleukin-1β (IL-1β) competitively bound to the microRNA miR-138 in the lungs of bacterially infected mice. Initially, more

  • Controlled activation

    T Cell Activation At the intestinal barrier, lymphocyte activation is a tightly regulated process that enables rapid responses to pathogens but avoids destructive inflammation. Konjar et al. examined how intraepithelial lymphocytes (IELs) maintain a controlled activation state, which is influenced more

  • Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor [Immunology and Inflammation]

    The inflammasomes are signaling platforms that promote the activation of inflammatory caspases such as caspases-1, -4, -5, and -11, which cleave gasdermin D (GSDMD) to induce pyroptotic cell death. The mechanisms of GSDMD recognition by inflammatory caspases remain poorly understood. Here, we demons more

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Definition

Inflammation

Inflammation on the skin, showing the redness and swelling characteristic of inflammation (presents as darkening in people with dark skin). Black rings of necrotic tissue surround central areas of pus Inflammation (Latin , inflammatio, to set ... more

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