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Inflammation

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The Chemistry of Stinging Nettles

Doubtless the majority of people reading this will, at some point in their life, have had the unpleasant experience of being stung by stinging nettles. But what chemicals do stinging nettles contain that elicit this effect? Further to that, a commonly espoused remedy for the stings, in the UK at lea more

Publications Inflammation

  • Inflammatory decoy control

    Sepsis Bacterial infection can lead to sepsis, inflammation, and death. Li et al. found that the long noncoding RNA MEG3-4 and the mRNA encoding the proinflammatory cytokine interleukin-1β (IL-1β) competitively bound to the microRNA miR-138 in the lungs of bacterially infected mice. Initially, more

  • Controlled activation

    T Cell Activation At the intestinal barrier, lymphocyte activation is a tightly regulated process that enables rapid responses to pathogens but avoids destructive inflammation. Konjar et al. examined how intraepithelial lymphocytes (IELs) maintain a controlled activation state, which is influenced more

  • Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor [Immunology and Inflammation]

    The inflammasomes are signaling platforms that promote the activation of inflammatory caspases such as caspases-1, -4, -5, and -11, which cleave gasdermin D (GSDMD) to induce pyroptotic cell death. The mechanisms of GSDMD recognition by inflammatory caspases remain poorly understood. Here, we demons more

All publications on inflammation
Definition

Inflammation

Inflammation on the skin, showing the redness and swelling characteristic of inflammation (presents as darkening in people with dark skin). Black rings of necrotic tissue surround central areas of pus Inflammation (Latin , inflammatio, to set ... more

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