Immunoglobulins

In persons with a severe allergy to bee or wasp venom, the bite of just one insect can even be fatal when it triggers acute respiratory distress and circulatory failure. A project funded by the FWF is working on vaccines that contain components of the insect venom in an attenuated form with signific more

Differences in production methods for therapeutic antibodies can lead to variations in their structure, depending on the recombinant procedure selected. The distinctions, which are based on a number of glycosylations, even impact antibodies’ stability. This was the result of a high-precision compari more

Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune disorder X-linked severe combined immunodeficiency disorder. Preliminary results from the ongoing, multicenter study were included in the more

Immunoglobulins or antibodies are proteins that are involved in the immune response. That makes them interesting drug targets. This application note shows the detection of the immunoglobulin IgG using an AlphaLISA® assay performed on BMG LABTECH's PH more

SPARCL refers to an immunoassay that does not require washing steps more

by Ming Chang, Yaw-Jen Chang, Pei Yu Chao, Qing Yu Cancer cells secrete many exosomes, which facilitate metastasis and the later growth of cancer. For early cancer diagnosis, the detection of exosomes is a crucial step. Exosomes exist in biological fluid, such as blood, which contains various pro more

Marine Drugs, Vol. 16, Pages 181: Anti-Aging Effect of Chitosan Oligosaccharide on d-Galactose-Induced Subacute Aging in Mice Marine Drugs doi: 10.3390/md16060181 Authors: Song-Zhi Kong Ji-Cheng Li Si-Dong Li Ming-Neng Liao Cheng-Peng Li Pin-Jin Zheng Min-Hui Guo Wei-Xiang Tan more

Publication date: 15 June 2018 Source:European Journal of Pharmaceutical Sciences, Volume 118 Author(s): Isaac R. Melamed, Michael Borte, Laurenz Trawnicek, Ai-Lan Kobayashi, Roger H. Kobayashi, Alan Knutsen, Sudhir Gupta, William Smits, Anna Pituch-Noworolska, Magdalena St more