Libraries for Proteins

Dynamic combinatorial libraries generated from hydrazone-functionalized surface mimetics

29-May-2018 - Combinatorial libraries are a key component of the chemist's toolkit for ligand screening. Dynamic combinatorial libraries add a new dimension by interlinking synthesis and screening. Now, British scientists have developed a dynamic combinatorial library for the screening of supramolecular ligand ...

Towards more effective therapies to fight breast cancer

22-May-2017 - Breast cancer is one of the most common cancers in women in Italy and in the world. Today, however, it seems possible to design more selective and effective drugs through numerical simulations. This is what has been revealed by research carried out by the "Istituto Officina dei Materiali" (IOM) ...

Hydrophobic proteins on virus surfaces can help purify vaccines

27-Mar-2017 - A person doesn't have to get sick to catch a virus. Researchers hope to catch viruses for detection and vaccinations by understanding their sticky outer layers. The complex structures making the surface of a virus are small weaves of proteins that make a big impact on how a virus interacts with ...

MIT researchers develop a better way to grow stem cells

23-Aug-2010 - Human pluripotent stem cells, which can become any other kind of body cell, hold great potential to treat a wide range of ailments, including Parkinson's disease, multiple sclerosis and spinal cord injuries. However, scientists who work with such cells have had trouble growing large enough ...

MIT: Extending the shelf life of antibody drugs

New model allows researchers to design more stable drugs

01-Jul-2009 - A new computer model developed at MIT can help solve a problem that has plagued drug companies trying to develop promising new treatments made of antibodies: Such drugs have a relatively short shelf life because they tend to clump together, rendering them ineffective. Antibodies are the most ...

Transport behavior of E. coli varies depending on manure source

Scientists collaborate, measuring cell properties to decipher why some E. coli strains travel farther than others

11-Mar-2009 - Escherichia coli is a commonly used indicator organism for detecting the presence of fecal contamination in drinking water supplies. The importance of E. coli as an indicator organism has led to several studies looking at the transport behavior of this important microorganism in groundwater ...