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Biomol GmbH, Germany

Biomol GmbH offers antibodies, enzymes, bioactive lipids, microarrays and reagents for biomedical research. Our focus is on cellular regulation and signal transduction. Together with our partners, we also provide a variety of specialized kits for drug discovery. more

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Biophysical characterization of epigenetic interactions and associated drug discovery, using Isothermal Titration Calorimetry

The term ‘epigenetics’ refers to changes in and regulation of gene expression and function, without alteration of DNA sequence. The mechanisms behind these changes involve “epigenetic regulator” proteins that interact with and modify chromatin (DNA wrapped around histone proteins). Epigenetic regula

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Histone In biology , histones are the chief protein components of chromatin . They act as spools around which DNA winds, and they play a role in gene regulation . Classes Six major histone classes are known: :* H1 (sometimes called the lin ... more


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