Largest Diphtheria Outbreak in Western Europe in 70 Years

Study Traces Transmission Routes

06-Jun-2025 - In 2022, Western Europe experienced the largest surge in reported diphtheria infections in 70 years. Clinical and genomic data from the outbreak point toward transmission routes along established migration pathways into Europe. Rapid interventions successfully contained the outbreak, yet strains ...

Know thy enemy

Kill MRSA with tailored chemistry

22-Dec-2016 - UConn medicinal chemists have developed experimental antibiotics that kill MRSA, a common and often deadly bacteria that causes skin, lung, and heart infections. The success is due to their strategy, which found a weakness and exploited it in a way the bacteria should have trouble ...

Bacterial defense policies

14-Oct-2014 - High-resolution cryo-electron microscopy has now revealed in unprecedented detail the structural changes in the bacterial ribosome which results in resistance to the antibiotic erythromycin. Multiresistant bacterial pathogens that are insensitive to virtually all available antibiotics are one of ...

Erythromycin A produced in E. coli for first time

26-Nov-2010 - Researchers at Tufts University School of Engineering have reported the first successful production of the antibiotic erythromycin A, and two variations, using E. coli as the production host. The work, published in the November 24, 2010, issue of Chemistry and Biology, offers a more ...

Arpida adds novel antibiotic AR-2474 to its preclinical pipeline

12-Mar-2007 - Arpida Ltd. announced positive results of in vitro microbiological studies with AR-2474 against a large panel of clinical isolates, including those resistant to various current therapies. In addition, topical applications of AR-2474 were found to be highly effective in eradicating methicillin ...