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Neonatal onset multisystem inflammatory disease
Neonatal onset multisystem inflammatory disease (also known as NOMID, Chronic Neurologic Cutaneous and Articular Syndrome, or CINCA) is a rare genetic periodic fever syndrome which causes uncontrolled inflammation in multiple parts of the body starting in the newborn period. Symptoms include skin rashes, severe arthritis, and chronic meningitis leading to neurologic damage.
Additional recommended knowledge
NOMID can result from a mutation in the CIAS1 gene, which helps control inflammation. Mutations in this gene also cause familial cold urticaria and Muckle-Wells syndrome. NOMID has been successfully treated with the drug anakinra.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Neonatal_onset_multisystem_inflammatory_disease". A list of authors is available in Wikipedia.|